Benchmarking bioinformatics approaches for tumour mutational burden evaluation from a large cancer panel against whole-exome sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pathology"
DOI: 10.1136/jcp-2022-208385
Abstract: Tumour mutational burden (TMB) is used to predict response to immunotherapies. Although several groups have proposed calculation methods for TMB, a clear consensus has not yet emerged. In this study, we explored TMB calculation approaches… read more here.
Keywords: cancer panel; tumour mutational; whole exome; panel ... See more keywords
A TOP2A-derived cancer panel drives cancer progression in papillary renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology letters"
DOI: 10.3892/ol.2018.9179
Abstract: The aim of the present study was to investigate the function of the DNA topoisomerase IIα (TOP2A) gene and its associated genes in the progression of papillary renal cell carcinoma (PRCC). Online cancer databases, including… read more here.
Keywords: cancer; top2a; renal cell; cancer panel ... See more keywords