Prevalence of pathogenic variants in cancer-predisposing genes in second cancer after childhood solid cancers.
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DOI: 10.1002/cam4.5835
Abstract: Second malignant neoplasms (SMNs) are one of the most severe late complications after pediatric cancer treatment. However, the effect of genetic variation on SMNs remains unclear. In this study, we revealed germline genetic factors that… read more here.
Keywords: pathogenic variants; prevalence pathogenic; variants cancer; cancer predisposing ... See more keywords
Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene
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DOI: 10.3390/genes14020277
Abstract: FANCI was recently identified as a new candidate ovarian cancer (OC)-predisposing gene from the genetic analysis of carriers of FANCI c.1813C>T; p.L605F in OC families. Here, we aimed to investigate the molecular genetic characteristics of… read more here.
Keywords: ovarian cancer; cancer predisposing; fanci 1813c; predisposing gene ... See more keywords