Abstract 1881: Bimodality in pan-cancer proteomics reveals new biomarker discovery opportunities
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-1881
Abstract: Bimodal protein expression, characterized by a protein distribution with two modes, is linked to phenotypic variation across various biological systems. While previous studies focused on RNA expression data, we developed a bimodality model tailored for… read more here.
Keywords: cancer; proteomics reveals; bimodality pan; pan cancer ... See more keywords
Computational Advances in the Label-free Quantification of Cancer Proteomics Data.
Sign Up to like & getrecommendations! Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/1381612824666181102125638
Abstract: BACKGROUND Due to its ability to provide quantitative and dynamic information on tumor genesis and development by directly profiling protein expression, the proteomics has become intensely popular for characterizing the functional proteins driving the transformation… read more here.
Keywords: proteomics data; cancer proteomics; free quantification; label free ... See more keywords
Cancer Proteomics for Cellular Dysfunction: Insights and Trends.
Sign Up to like & getrecommendations! Published in 2023 at "Current pharmaceutical design"
DOI: 10.2174/1381612829666230316110932
Abstract: BACKGROUND Cancer is an ailment with having a very low survival rate globally. Poor cancer prognosis is primarily caused by the fact that people are found to have the disease when it is already well… read more here.
Keywords: cancer proteomics; proteomics cellular; applications proteomics; dysfunction insights ... See more keywords
Prognostic Protein Biomarker Screening for Thyroid Carcinoma Based on Cancer Proteomics Profiles
Sign Up to like & getrecommendations! Published in 2024 at "Biomedicines"
DOI: 10.3390/biomedicines12092066
Abstract: Thyroid carcinoma (THCA) ranks among the most prevalent cancers globally. Integrating advanced genomic and proteomic analyses to construct a protein-based prognostic model promises to identify effective biomarkers and explore new therapeutic avenues. In this study,… read more here.
Keywords: cancer proteomics; prognostic protein; cancer; thyroid carcinoma ... See more keywords