The Role of Alternative Splicing in Cancer: Regulatory Mechanism, Therapeutic Strategy, and Bioinformatics Application.
Sign Up to like & getrecommendations! Published in 2022 at "DNA and cell biology"
DOI: 10.1089/dna.2022.0322
Abstract: [Formula: see text] Alternative splicing (AS) can generate distinct transcripts and subsequent isoforms that play differential functions from the same pre-mRNA. Recently, increasing numbers of studies have emerged, unmasking the association between AS and cancer.… read more here.
Keywords: role alternative; biology; cancer regulatory; alternative splicing ... See more keywords
LINC00324 in cancer: Regulatory and therapeutic implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.1039366
Abstract: LINC00324 is a 2082 bp intergenic noncoding RNA. Aberrant expression of LINC00324 was associated with the risk of 11 tumors and was closely associated with clinicopathological features and prognostic levels of 7 tumors. LINC00324 can… read more here.
Keywords: regulatory therapeutic; signaling pathway; linc00324; linc00324 cancer ... See more keywords
The Regulatory Network of MicroRNA in the Metabolism of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.61618
Abstract: Colorectal cancer (CRC) is the third most common malignant tumor in the world. During the progression of CRC, the entire metabolic network undergoes reprogramming, including marked changes in the regulation of glucose, lipid and amino… read more here.
Keywords: cancer; cancer regulatory; regulatory network; metabolism ... See more keywords