Organoids in pediatric cancer research.
Sign Up to like & getrecommendations! Published in 2025 at "FEBS letters"
DOI: 10.1002/1873-3468.70188
Abstract: Over the past decade, organoid technology has emerged as a transformative tool in biomedical research, enabling the development of physiologically relevant models of both healthy and malignant tissues. While this technology has substantially advanced our… read more here.
Keywords: technology; organoids pediatric; pediatric cancer; research ... See more keywords
Fibrosis‐Encapsulated Tumoroid, A Solid Cancer Assembloid Model for Cancer Research and Drug Screening
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202402391
Abstract: Peritumoral fibrosis is known to promote cancer progression and confer treatment resistance in various solid tumors. Consequently, developing accurate cancer research and drug screening models that replicate the structure and function of a fibrosis‐surrounded tumor… read more here.
Keywords: research drug; cancer; fibrosis; cancer research ... See more keywords
Engaging Under‐Represented Adolescents and Young Adults in Cancer Research: A Qualitative Exploration of Lived Experiences and Engagement Strategies
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Medicine"
DOI: 10.1002/cam4.71086
Abstract: Adolescents and young adults (AYAs; 15–39 years) diagnosed with cancer face unique challenges during and after treatment, which have implications for improving cancer care. However, AYA cancer research is limited by the under‐representation of those who… read more here.
Keywords: cancer; lived experiences; adolescents young; young adults ... See more keywords
A guide to large data sets for population‐based cancer research: Strengths, limitations, and pitfalls
Sign Up to like & getrecommendations! Published in 2024 at "Cancer"
DOI: 10.1002/cncr.35535
Abstract: With the proliferation of cancer research based on large databases, misalignment of research questions and data set capabilities is inevitable. Nationally maintained databases are appealing to cancer researchers because of the ease of access to… read more here.
Keywords: cancer; data sets; research; cancer research ... See more keywords
The impact of focused federal initiatives on pediatric cancer research
Sign Up to like & getrecommendations! Published in 2025 at "Cancer"
DOI: 10.1002/cncr.70172
Abstract: Federal initiatives, including the Childhood Cancer Data Initiative and the Childhood Cancer Survivorship, Treatment, Access, and Research Act, are advancing pediatric cancer data sharing and strengthening infrastructure required for clinical trials, biobanking, and biospecimen collection.… read more here.
Keywords: cancer; pediatric cancer; impact focused; cancer research ... See more keywords
Real-world Overall Survival Using Oncology Electronic Health Record Data: Friends of Cancer Research Pilot.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical pharmacology and therapeutics"
DOI: 10.1002/cpt.2443
Abstract: In prior work, Friends of Cancer Research convened multiple data partners to establish standardized definitions for oncology real-world endpoints derived from electronic health records (EHR) and claims data. Here, we assessed the performance of real-world… read more here.
Keywords: friends cancer; real world; oncology; cancer research ... See more keywords
Research advances in nanomedicine applied to the systemic treatment of colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34256
Abstract: The systematic treatment of colorectal cancer (CRC) still has room for improvement. The efficacy of chemotherapy, that of anti‐vascular therapy, and that of immunotherapy have been unsatisfactory. In recent years, nanomaterials have been used as… read more here.
Keywords: treatment colorectal; cancer research; colorectal cancer; treatment ... See more keywords
Global colorectal cancer research, 2007‐2021: Outputs and funding
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Cancer"
DOI: 10.1002/ijc.34279
Abstract: The purpose of this study was to provide an evidence base for colorectal cancer research activity that might influence policy, mainly at the national level. Improvements in healthcare delivery have lengthened life expectancy, but within… read more here.
Keywords: cancer research; research; 2007 2021; funding global ... See more keywords
NMR-Based Metabolomics in Gallbladder Cancer Research.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9690-2_14
Abstract: Gallbladder cancer (GBC) is a common form of malignancy, which has high incidence rates in the northern parts of India, South America, Japan, and in Native American populations. A few metabolomic studies have revealed changes… read more here.
Keywords: metabolomics gallbladder; cancer research; based metabolomics; cancer ... See more keywords
NMR-Based Metabolomics in Cancer Research.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-51652-9_14
Abstract: Nuclear magnetic resonance (NMR) spectroscopy offers reproducible quantitative analysis and structural identification of metabolites in various complex biological samples, such as biofluids (plasma, serum, and urine), cells, tissue extracts, and even intact organs. Therefore, NMR-based… read more here.
Keywords: metabolomics cancer; cancer research; nmr based; based metabolomics ... See more keywords
Spatial transcriptomics in cancer research and potential clinical impact: a narrative review
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-024-05816-0
Abstract: Spatial transcriptomics (ST) provides novel insights into the tumor microenvironment (TME). ST allows the quantification and illustration of gene expression profiles in the spatial context of tissues, including both the cancer cells and the microenvironment… read more here.
Keywords: oncology; cancer; spatial transcriptomics; review ... See more keywords