Sonosensitizer-Functionalized Graphene Nanoribbons for Adhesion Blocking and Sonodynamic Ablation of Ovarian Cancer Spheroids.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202001368
Abstract: Advanced stage ovarian cancer is challenging to treat due to widespread seeding of tumor spheroids throughout the mesothelial lining of the peritoneal cavity. In this work, a therapeutic strategy using graphene nanoribbons (GNR) functionalized with… read more here.
Keywords: cancer spheroids; peg ce6; gnr peg; ovarian cancer ... See more keywords
Autonomous Microlasers for Profiling Extracellular Vesicles from Cancer Spheroids.
Sign Up to like & getrecommendations! Published in 2023 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c04123
Abstract: Self-propelled micro/nanomotors are emergent intelligent sensors for analyzing extracellular biomarkers in circulating biological fluids. Conventional luminescent motors are often masked by a highly dynamic and scattered environment, creating challenges to characterize biomarkers or subtle binding… read more here.
Keywords: autonomous microlasers; profiling extracellular; extracellular vesicles; microlasers profiling ... See more keywords
High-Resolution In Situ High-Content Imaging of 3D-Bioprinted Single Breast Cancer Spheroids for Advanced Quantification of Benzo(a)pyrene Carcinogen-Induced Breast Cancer Stem Cells.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c17877
Abstract: Cancer stem cells (CSCs), also known as tumor-initiating cells, are critically correlated with carcinogenesis and are strongly affected by the environmental factors. Environmental carcinogens, such as benzo(a)pyrene (BaP), are associated with the overproduction of CSCs… read more here.
Keywords: cancer stem; breast; breast cancer; cscs ... See more keywords
Abstract B14: Atovaquone targets STAT3 in ovarian cancer spheroids
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.ovca19-b14
Abstract: Ovarian cancer remains a deadly disease for countless women. Recent evidence demonstrates that ovarian cancer cell clusters, spheroids, are important in promoting ovarian recurrence and metastasis. Often these spheroids are resistant to therapy. Therefore, we… read more here.
Keywords: cancer spheroids; stat3 ovarian; ovarian cancer; cancer ... See more keywords
Analysis of inflammatory signatures of cancer spheroids in blood and their role in metastasis.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.3090
Abstract: 3090Background: Cancer mortality correlates with metastatic progression where genetic/epigenetic changes in the cancer are important. Recent data indicate, however, that the host thrombotic and inf... read more here.
Keywords: analysis inflammatory; spheroids blood; cancer spheroids; signatures cancer ... See more keywords
Morphological Response in Cancer Spheroids for Screening Photodynamic Therapy Parameters
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.784962
Abstract: Photodynamic therapy (PDT) is a treatment which uses light-activated compounds to produce reactive oxygen species, leading to membrane damage and cell death. Multicellular cancer spheroids are a preferable alternative for PDT evaluation in comparison to… read more here.
Keywords: cancer spheroids; response; cell; photodynamic therapy ... See more keywords
A SMYD3/ITGB6/TGFβ1 Positive Feedback Loop Promotes the Invasion and Adhesion of Ovarian Cancer Spheroids
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.690618
Abstract: Background Implantation metastasis is the main means of dissemination in ovarian cancer. Our previous studies showed that SET and MYND domain-containing protein 3 (SMYD3) expression was higher in ovarian cancer spheroids than in monolayers. SMYD3… read more here.
Keywords: cancer spheroids; tgf; ovarian cancer; invasion adhesion ... See more keywords
The New Serum-Free OptiPASS® Medium in Cold and Oxygen-Free Conditions: An Innovative Conservation Method for the Preservation of MDA-MB-231 Triple Negative Breast Cancer Spheroids
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13081945
Abstract: Simple Summary Cancer spheroids are reproducible and relevant multicellular in vitro preclinical models. Thus, their use is required more and more for drug development processes in oncology in order to improve the prediction of anticancer… read more here.
Keywords: storage; negative breast; cancer spheroids; breast cancer ... See more keywords
Metabolic Reprogramming of Ovarian Cancer Spheroids during Adhesion
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061399
Abstract: Simple Summary During metastasis, ovarian cancer spheroids move from the original tumor and travel through the abdominal cavity to other sites. During the movement of spheroids, cells are exposed to an environment with little oxygen… read more here.
Keywords: cancer; metabolism; adhesion; metastasis ... See more keywords