Cancer‐associated fibroblast migration in non‐small cell lung cancers is modulated by increased integrin α11 expression
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12937
Abstract: Cancer‐associated fibroblasts (CAFs) regulate cancer progression through the modulation of extracellular matrix (ECM) and cancer cell adhesion. While undergoing a series of phenotypic changes, CAFs control cancer–stroma interactions through integrin receptor signaling. Here, we isolated… read more here.
Keywords: cancer stroma; expression; non small; cancer ... See more keywords
Quantifying heterogeneity to drug response in cancer-stroma kinetics.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2122352120
Abstract: A crucial challenge in medicine is choosing which drug (or combination) will be the most advantageous for a particular patient. Usually, drug response rates differ substantially, and the reasons for this response unpredictability remain ambiguous.… read more here.
Keywords: cancer stroma; response; drug; drug response ... See more keywords
Pancreatic cancer stroma: controversies and current insights
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DOI: 10.1080/00365521.2017.1293726
Abstract: Abstract Pancreatic cancer is characterized by a dense stromal response. The stroma includes a heterogeneous mass of cells, including pancreatic stellate cells, fibroblasts, immune cells and nerve cells, as well as extracellular matrix proteins, cytokines… read more here.
Keywords: stroma controversies; pancreatic cancer; stroma; cancer stroma ... See more keywords
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v29.i17.2701
Abstract: Several studies have shown that the immune system is highly regulated by tryptophan metabolism, which serves as an immunomodulatory factor. The indoleamine 2,3-dioxygenase 1 (IDO1), as an intracellular enzyme that participates in metabolism of the… read more here.
Keywords: metabolism; tryptophan metabolism; pancreatic cancer; cancer stroma ... See more keywords
Overexpression of miR‑221 and miR‑222 in the cancer stroma is associated with malignant potential in colorectal cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Oncology reports"
DOI: 10.3892/or.2018.6575
Abstract: The cancer stroma is important in cancer development, however, whether the aberrant expression of microRNAs (miRNAs) in the cancer stroma is associated with cancer progression remains to be fully elucidated. The aim of the present… read more here.
Keywords: mir 222; mir 221; stroma; cancer stroma ... See more keywords