Hedgehog-mesenchyme gene signature identifies bi-modal prognosis in luminal and basal breast cancer sub-types.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00416h
Abstract: Hedgehog signaling (Hh) has been shown to be hyper-activated in several cancers. However, active Hh signaling can promote or inhibit tumor growth; thus identification of markers beyond main canonical Hh target genes is needed to… read more here.
Keywords: cancer; gene; cancer sub; breast cancer ... See more keywords
Cancer in sub-Saharan Africa
Sign Up to like & getrecommendations! Published in 2020 at "Science"
DOI: 10.1126/science.aay4743
Abstract: Knowledge of cancer in Africa brings needed diversity to improve health worldwide Cancer is an increasing global public health burden. This is especially the case in sub-Saharan Africa (SSA); high rates of cancer—particularly of the… read more here.
Keywords: knowledge; cancer sub; sub saharan; epidemiology ... See more keywords
Explaining the aggressiveness of breast cancer in sub-Saharan African patients
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2019-206071
Abstract: The incidence of breast cancer (BC) in sub-Saharan Africa is projected to double between 2016 and 2035. The control of the disease in the region will become an increasingly critical challenge.1 Comprehensive prevention, detection and… read more here.
Keywords: breast cancer; cancer sub; pathology; sub saharan ... See more keywords
DeepTRIAGE: interpretable and individualised biomarker scores using attention mechanism for the classification of breast cancer sub-types
Sign Up to like & getrecommendations! Published in 2020 at "BMC Medical Genomics"
DOI: 10.1186/s12920-020-0658-5
Abstract: Background Breast cancer is a collection of multiple tissue pathologies, each with a distinct molecular signature that correlates with patient prognosis and response to therapy. Accurately differentiating between breast cancer sub-types is an important part… read more here.
Keywords: cancer; sub types; biomarker scores; cancer sub ... See more keywords