The influence of breast cancer subtype on survival after palliative radiation for osseous metastases
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3597
Abstract: Among patients with osseous metastases, breast cancer (BC) patients typically have the best prognosis. In the palliative setting, BC is often considered a single disease, but based on receptor status there are four distinct subtypes:… read more here.
Keywords: cancer subtype; breast cancer; osseous metastases; cancer ... See more keywords
Divergence of mutational signatures in association with breast cancer subtype
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23461
Abstract: Abnormal molecular processes occurring throughout the genome leave distinct somatic mutational patterns termed mutational signatures. Exploring the associations between mutational signatures and clinicopathological features can unravel potential mechanisms driving tumorigenic processes. read more here.
Keywords: cancer subtype; signatures association; divergence mutational; breast cancer ... See more keywords
Pseudogene Profiling for Cancer Subtype Classification.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1503-4_19
Abstract: Although long thought of as "gene relics," pseudogenes have recently gained research and medical interests because of their potential impacts on cellular pathways and of their clinical relevance. Studies have profiled pseudogenes at both DNA… read more here.
Keywords: pseudogene profiling; cancer subtype; subtype classification;
A high-risk luminal A dominant breast cancer subtype with increased mobility
Sign Up to like & getrecommendations! Published in 2019 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-019-05135-w
Abstract: PurposeBreast cancer is a heterogeneous disease, and although advances in molecular subtyping have been achieved in recent years, most subtyping strategies target individual genes independent of one another and primarily concentrate on proliferative markers. The… read more here.
Keywords: cancer; high risk; cancer subtype; breast cancer ... See more keywords
BMI, physical activity, and breast cancer subtype in white, black, and Sea Island breast cancer survivors.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in cancer research"
DOI: 10.1016/bs.acr.2020.01.005
Abstract: Higher BMI, lower rates of physical activity (PA), and hormone receptor-negative breast cancer (BC) subtype are associated with poorer BC treatment outcomes. We evaluated the prevalence of high BMI, low PA level, and BC subtype… read more here.
Keywords: cancer subtype; breast cancer; cancer; physical activity ... See more keywords
SubtypeDrug: a software package for prioritization of candidate cancer subtype-specific drugs
Sign Up to like & getrecommendations! Published in 2021 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btab011
Abstract: SUMMARY Cancer can be classified into various subtypes by its molecular, histological, or clinical characteristics. Discovering cancer-subtype-specific drugs is a crucial step in personalized medicine. SubtypeDrug is a system biology R-based software package that enables… read more here.
Keywords: package; specific drugs; subtype specific; cancer subtype ... See more keywords
Lung cancer subtype diagnosis using weakly-paired multi-omics data
Sign Up to like & getrecommendations! Published in 2022 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btac643
Abstract: MOTIVATION Cancer subtype diagnosis is crucial for its precise treatment and different subtypes need different therapies. Although the diagnosis can be greatly improved by fusing multi-omics data, most fusion solutions depend on paired omics data,… read more here.
Keywords: diagnosis; multi omics; cancer subtype; omics data ... See more keywords
Low-Rank Joint Subspace Construction for Cancer Subtype Discovery
Sign Up to like & getrecommendations! Published in 2020 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2019.2894635
Abstract: Multimodal data integration is an important framework for cancer subtype discovery as it can blend the inherent properties of individual modalities with their cross-platform correlations to infer clinically relevant subtypes. The main problem here is… read more here.
Keywords: cancer subtype; subtype discovery; low rank; joint subspace ... See more keywords
Multiview Robust Graph-Based Clustering for Cancer Subtype Identification
Sign Up to like & getrecommendations! Published in 2022 at "IEEE/ACM Transactions on Computational Biology and Bioinformatics"
DOI: 10.1109/tcbb.2022.3143897
Abstract: Cancer subtype identification is to classify cancer into groups according to their molecular characteristics and clinical manifestations and is the basis for more personalized diagnosis and therapy. Public datasets such as The Cancer Genome Atlas… read more here.
Keywords: cancer subtype; subtype identification; graph; graph based ... See more keywords
Integrative subspace clustering by common and specific decomposition for applications on cancer subtype identification
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medical Genomics"
DOI: 10.1186/s12920-019-0633-1
Abstract: Recent high throughput technologies have been applied for collecting heterogeneous biomedical omics datasets. Computational analysis of the multi-omics datasets could potentially reveal deep insights for a given disease. Most existing clustering methods by multi-omics data… read more here.
Keywords: cancer; decomposition; cancer subtype; subtype identification ... See more keywords
MoGCN: A Multi-Omics Integration Method Based on Graph Convolutional Network for Cancer Subtype Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.806842
Abstract: In light of the rapid accumulation of large-scale omics datasets, numerous studies have attempted to characterize the molecular and clinical features of cancers from a multi-omics perspective. However, there are great challenges in integrating multi-omics… read more here.
Keywords: network; multi omics; cancer subtype; mogcn ... See more keywords