Seventeen primary malignant neoplasms involving the skin, ovary, esophagus, colon, oral cavity, and ear canal: a case report and review of the literature
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Journal of Gastroenterology"
DOI: 10.1007/s12328-021-01444-0
Abstract: Multiple primary malignant neoplasm (MPMN) is a rare disease with two or more malignant neoplasms in one patient. In less than 0.1% of cancer patients, four or more occur. MPMN is frequently associated with hereditary… read more here.
Keywords: malignant neoplasms; hereditary cancer; primary malignant; case ... See more keywords
A mechanism for the tissue specificity in BAP1 cancer syndrome
Sign Up to like & getrecommendations! Published in 2019 at "Translational cancer research"
DOI: 10.21037/tcr.2019.06.41
Abstract: Cancer predisposition syndromes are caused by inherited mutations in tumor suppressor genes. Remarkably, despite the presence of the faulty tumor suppressor gene in virtually every cell in the body, individuals with a cancer predisposition syndrome… read more here.
Keywords: bap1 cancer; mechanism tissue; tissue specificity; specificity bap1 ... See more keywords
Unexpected Findings in Hereditary Breast and Ovarian Cancer Syndrome: Low-Level Constitutional Mosaicism in BRCA2
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020502
Abstract: Hereditary breast and ovarian cancer syndrome (HBOC) is a clinical entity characterized by an increased risk of developing breast and ovarian cancer. The genetic diagnosis is based on the identification of heterozygous germinal variants in… read more here.
Keywords: ovarian cancer; breast ovarian; constitutional mosaicism; cancer syndrome ... See more keywords