Advocating for equitable management of hereditary cancer syndromes.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of genetic counseling"
DOI: 10.1002/jgc4.1548
Abstract: The potential for preventive medicine to lead to more equitable health outcomes exists with the inclusion of genetic testing in medicine. Because of the medical implications of genetic testing for hereditary cancer syndromes and the financial… read more here.
Keywords: cancer; medicine; cancer syndromes; access ... See more keywords
Clinical outcomes of preimplantation genetic testing for hereditary cancer syndromes: A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Prenatal Diagnosis"
DOI: 10.1002/pd.6084
Abstract: To conduct a systematic review of the published literature on clinical outcomes following preimplantation genetic testing for monogenic disorders (PGT‐M) for hereditary cancer syndromes (HCS). read more here.
Keywords: clinical outcomes; preimplantation genetic; genetic testing; systematic review ... See more keywords
Implementation of massive sequencing in the genetic diagnosis of hereditary cancer syndromes: diagnostic performance in the Hereditary Cancer Programme of the Valencia Community (FamCan-NGS)
Sign Up to like & getrecommendations! Published in 2019 at "Hereditary Cancer in Clinical Practice"
DOI: 10.1186/s13053-019-0104-x
Abstract: BackgroundApproximately 5 to 10% of all cancers are caused by inherited germline mutations, many of which are associated with different Hereditary Cancer Syndromes (HCS). In the context of the Program of Hereditary Cancer of the… read more here.
Keywords: hereditary cancer; genetic diagnosis; valencia community; cancer syndromes ... See more keywords
Renal Cell Cancer Syndromes: Identification and Management of Patients and Families at Increased Risk.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical journal of oncology nursing"
DOI: 10.1188/20.cjon.356-359
Abstract: There are many inherited renal cell cancer syndromes that increase an individual's risk of developing renal cell cancer. The age of onset for these renal cell cancer syndromes ranges from infancy to age 65 years.… read more here.
Keywords: cell cancer; cancer syndromes; renal cell; risk ... See more keywords
Hereditary Gynecologic Cancer Syndromes – A Narrative Review
Sign Up to like & getrecommendations! Published in 2022 at "OncoTargets and therapy"
DOI: 10.2147/ott.s353054
Abstract: Abstract Hereditary cancer syndromes are defined as syndromes, where the genetics of cancer are the result of low penetrant polymorphisms or of a single gene disorder inherited in a mendelian fashion. During the last decade,… read more here.
Keywords: review; hereditary gynecologic; ovarian cancer; syndrome ... See more keywords
Pathogenic Variant Profile of Hereditary Cancer Syndromes in a Vietnamese Cohort
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.789659
Abstract: Background Hereditary cancer syndromes (HCS) are responsible for 5-10% of cancer cases. Genetic testing to identify pathogenic variants associated with cancer predisposition has not been routinely available in Vietnam. Consequently, the prevalence and genetic landscape… read more here.
Keywords: cancer; genetic testing; variant; cancer syndromes ... See more keywords
Cancer and Radiosensitivity Syndromes: Is Impaired Nuclear ATM Kinase Activity the Primum Movens?
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14246141
Abstract: Simple Summary A review of the molecular and cellular features of the major cancer syndromes associated with radiosensitivity revealed the importance of the ATM protein, either as an impaired kinase in the nucleus or as… read more here.
Keywords: cancer radiosensitivity; atm kinase; cancer syndromes; radiosensitivity ... See more keywords
Identification of Germline Variants in Patients with Hereditary Cancer Syndromes in Northeast Mexico
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14020341
Abstract: Hereditary cancer syndromes (HCS) are genetic diseases with an increased risk of developing cancer. This research describes the implementation of a cancer prevention model, genetic counseling, and germline variants testing in an oncologic center in… read more here.
Keywords: germline variants; hereditary cancer; cancer syndromes; genetic counseling ... See more keywords
Personalized Systemic Therapies in Hereditary Cancer Syndromes
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14030684
Abstract: Hereditary cancer syndromes are inherited disorders caused by germline pathogenic variants (PVs) that lead to an increased risk of developing certain types of cancer, frequently at an earlier age than in the rest of the… read more here.
Keywords: personalized systemic; hereditary cancer; cancer syndromes; therapies hereditary ... See more keywords
Hereditary Cancer Syndromes: A Comprehensive Review with a Visual Tool
Sign Up to like & getrecommendations! Published in 2023 at "Genes"
DOI: 10.3390/genes14051025
Abstract: Hereditary cancer syndromes account for nearly 10% of cancers even though they are often underdiagnosed. Finding a pathogenic gene variant could have dramatic implications in terms of pharmacologic treatments, tailored preventive programs, and familiar cascade… read more here.
Keywords: syndromes comprehensive; hereditary cancer; cancer syndromes; cancer ... See more keywords
Lifestyle Behavior Interventions for Preventing Cancer in Adults with Inherited Cancer Syndromes: Systematic Review
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph192114098
Abstract: (1) Background: The link between lifestyle behaviors and cancer risk is well established, which is important for people with personal/family history or genetic susceptibility. Genetic testing is not sufficient motivation to prompt healthier lifestyle behaviors.… read more here.
Keywords: inherited cancer; review; systematic review; risk ... See more keywords