Self‐Assembled Nanoparticles as Cancer Therapeutic Agents
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202001602
Abstract: Most therapeutic agents for cancer are currently suffering from the shortcomings of poor solubility, severe side effects, and multidrug resistance. Supramolecular self‐assembly (SSA) in nanomedicines is a promising way to overcome these obstacles due to… read more here.
Keywords: cancer; self assembled; assembled nanoparticles; therapeutic agents ... See more keywords
Ovarian Cancer: Therapeutic Strategies to Overcome Immune Suppression.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-73359-9_3
Abstract: Ovarian cancer generally escapes diagnosis until the advanced stages. High-grade serous ovarian cancer (HGSOC) is the most frequently occurring form of this malaise and is a disease which has the highest mortality rate of gynecologic… read more here.
Keywords: immune suppression; cancer therapeutic; ovarian cancer; biology ... See more keywords
The therapeutic potential of metformin in gastric cancer
Sign Up to like & getrecommendations! Published in 2019 at "Gastric Cancer"
DOI: 10.1007/s10120-019-00952-w
Abstract: Metformin is a biguanide molecule used since 1957 to treat type 2 diabetes patients. In addition to its hypoglycemic effects, epidemiological studies have shown that metformin can be associated with a decrease in cancer development… read more here.
Keywords: metformin gastric; gastric cancer; cancer therapeutic; cancer ... See more keywords
Synthesis of iron oxide nanocube patched Janus magnetic nanocarriers for cancer therapeutic applications.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc03614e
Abstract: Janus magnetic particles, which can be customized for various multifunctionalities, have promising potential for cancer therapeutic carriers. Herein we synthesized iron oxide nanocube (IONC) patched Janus magnetic nanocarriers (IONCs-P-JMNC) using emulsification and interface evaporation/assembly. Novel… read more here.
Keywords: janus magnetic; iron oxide; patched janus; cancer therapeutic ... See more keywords
Global longitudinal strain is a better metric than left ventricular ejection fraction: lessons learned from cancer therapeutic-related cardiac dysfunction.
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Cardiology"
DOI: 10.1097/hco.0000000000000716
Abstract: PURPOSE OF THE REVIEW This review aims to highlight the utility of global longitudinal strain (GLS) in cancer therapeutic-related cardiac dysfunction (CTRCD), with an attempt to stipulate that GLS might be a better measure than… read more here.
Keywords: cancer therapeutic; gls; dysfunction; longitudinal strain ... See more keywords
Therapeutic targeting of cellular stress responses in cancer
Sign Up to like & getrecommendations! Published in 2018 at "Thoracic Cancer"
DOI: 10.1111/1759-7714.12890
Abstract: Similar to bacteria, yeast, and other organisms that have evolved pathways to respond to environmental stresses, cancer cells develop mechanisms that increase genetic diversity to facilitate adaptation to a variety of stressful conditions, including hypoxia,… read more here.
Keywords: cancer therapeutic; therapeutic targeting; targeting cellular; cellular stress ... See more keywords
Proteoglycans and Immunobiology of Cancer—Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.00875
Abstract: Disparity during the resolution of inflammation is closely related with the initiation and progression of the tumorigenesis. The transformed cells, through continuously evolving interactions, participate in various exchanges with the surrounding microenvironment consisting of extracellular… read more here.
Keywords: proteoglycans immunobiology; immunobiology cancer; therapeutic implications; cancer therapeutic ... See more keywords
Hyperactivation of p21-Activated Kinases in Human Cancer and Therapeutic Sensitivity
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11020462
Abstract: Over the last three decades, p21-activated kinases (PAKs) have emerged as prominent intracellular nodular signaling molecules in cancer cells with a spectrum of cancer-promoting functions ranging from cell survival to anchorage-independent growth to cellular invasiveness.… read more here.
Keywords: activated kinases; cancer therapeutic; kinases human; p21 activated ... See more keywords
Profiling Prostate Cancer Therapeutic Resistance
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms19030904
Abstract: The major challenge in the treatment of patients with advanced lethal prostate cancer is therapeutic resistance to androgen-deprivation therapy (ADT) and chemotherapy. Overriding this resistance requires understanding of the driving mechanisms of the tumor microenvironment,… read more here.
Keywords: therapeutic resistance; cancer therapeutic; prostate cancer; resistance ... See more keywords