A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters
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DOI: 10.1016/j.cell.2019.08.018
Abstract: Most human protein-coding genes are regulated by multiple, distinct promoters, suggesting that the choice of promoter is as important as its level of transcriptional activity. However, while a global change in transcription is recognized as… read more here.
Keywords: pan cancer; transcriptome analysis; cancer transcriptome; cancer ... See more keywords
Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-1628
Abstract: FusionSeeker is a new method to discover gene fusions and reconstruct fused transcript sequences in long-read cancer transcriptome sequencing data to help identify novel gene fusions important for tumorigenesis and progression. read more here.
Keywords: read cancer; cancer transcriptome; transcriptome sequencing; gene ... See more keywords