Cancer: The Tumor-Driven Disease of the Host.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.06.016
Abstract: Tumors interact reciprocally with their hosts' physiology and metabolism, making cancer a systemic disease. In this issue of Cell Metabolism, Borniger et al. (2018) demonstrate this phenomenon by linking the endocrine control of food intake with… read more here.
Keywords: tumor driven; metabolism; cancer tumor; driven disease ... See more keywords
Enhanced anticancer effect of ROS-boosted photothermal therapy by using fucoidan-coated polypyrrole nanoparticles.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.10.091
Abstract: Nanomaterial mediated cancer/tumor photo driven hyperthermia has obtained great awareness. Nevertheless, it is a challenge for improving the hyperthermic temperature lacking resistance to stimulated thermal stress. We thus developed a bioinspired nano-platform utilizing inclusion complexation… read more here.
Keywords: anticancer effect; effect ros; cancer tumor; enhanced anticancer ... See more keywords
Serine hydroxymethyl transferase 1 stimulates pro-oncogenic cytokine expression through sialic acid to promote ovarian cancer tumor growth and progression
Sign Up to like & getrecommendations! Published in 2017 at "Oncogene"
DOI: 10.1038/onc.2017.37
Abstract: High-grade serous (HGS) ovarian cancer accounts for 90% of all ovarian cancer-related deaths. However, factors that drive HGS ovarian cancer tumor growth have not been fully elucidated. In particular, comprehensive analysis of the metabolic requirements… read more here.
Keywords: cancer; cancer tumor; ovarian cancer; tumor growth ... See more keywords
Tumor infiltrating lymphocyte stratification of prognostic staging of early-stage triple negative breast cancer
Sign Up to like & getrecommendations! Published in 2022 at "npj Breast Cancer"
DOI: 10.1038/s41523-021-00362-1
Abstract: The importance of integrating biomarkers into the TNM staging has been emphasized in the 8 th Edition of the American Joint Committee on Cancer (AJCC) Staging system. In a pooled analysis of 2148 TNBC-patients in… read more here.
Keywords: cancer; tumor infiltrating; breast cancer; cancer tumor ... See more keywords
Signaling new therapeutic opportunities: cytokines in prostate cancer
Sign Up to like & getrecommendations! Published in 2022 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2022.2108701
Abstract: ABSTRACT Introduction Despite FDA approval of sipuleucel-T in 2010, endeavors to use immune checkpoint inhibitors in unselected prostate cancer patients have not improved clinical outcomes. These efforts include studies with anti-PD1/PD-L1 and anti-CTLA-4 alone and… read more here.
Keywords: prostate cancer; signaling new; tumor microenvironment; cancer tumor ... See more keywords
Roles of Microbiota in Cancer: From Tumor Development to Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Oncology"
DOI: 10.1155/2022/3845104
Abstract: Cancer as a second leading cause of death arises from multifactorial pathology. The association of microbiota and their products with various pathologic conditions including cancer is receiving significant attention over the past few years. Mounting… read more here.
Keywords: cancer; microbiota cancer; tumor; tumor development ... See more keywords
Kindlin-3 in Immune Cells Is Required to Suppress Prostate Cancer Tumor Growth in Mice
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.15588
Abstract: Background/Aim: Kindlins are essential integrin activators. Kindlin-1 and kindlin-2 are often concomitantly expressed in epithelial tumor cells and participate in regulating tumor malignancy. However, it remains unclear whether kindlin-3, the one expressed in immune cells,… read more here.
Keywords: tumor growth; prostate cancer; cancer tumor; kindlin ... See more keywords
Modulation of Immune Infiltration of Ovarian Cancer Tumor Microenvironment by Specific Subpopulations of Fibroblasts
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12113184
Abstract: Simple Summary The ovarian cancer tumor microenvironment is made up of ovarian cancer cells along with a milieu of proteins and normal cells, including fibroblasts, immune cells, endothelial cells, pericytes and adipocytes. The noncancer components… read more here.
Keywords: cancer; cancer tumor; tumor microenvironment; ovarian cancer ... See more keywords
Looking at Thyroid Cancer from the Tumor-Suppressor Genes Point of View
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14102461
Abstract: Simple Summary Thyroid cancer is the most common endocrine cancer. As tumor-suppressor genes (TSGs) are implicated in many different functions in the organism, their loss in cells in a normal tissue may drive their transformation… read more here.
Keywords: thyroid cancer; cancer tumor; cancer; tumor suppressor ... See more keywords
Re-Shaping the Pancreatic Cancer Tumor Microenvironment: A New Role for the Metastasis Suppressor NDRG1
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15102779
Abstract: Simple Summary Pancreatic cancer remains the leading cause of cancer death globally. With no reliable early detection strategy and limited treatment options, up to 90% of patients will lose their lives to this disease. In… read more here.
Keywords: metastasis suppressor; pancreatic cancer; tumor microenvironment; cancer tumor ... See more keywords
The Dynamics of a Fractional-Order Mathematical Model of Cancer Tumor Disease
Sign Up to like & getrecommendations! Published in 2022 at "Symmetry"
DOI: 10.3390/sym14081694
Abstract: This article explores the application of the reduced differential transform method (RDTM) for the computational solutions of two fractional-order cancer tumor models in the Caputo sense: the model based on cancer chemotherapeutic effects which explain… read more here.
Keywords: cancer tumor; model; fractional order; tumor ... See more keywords