Biomaterial-Based In Situ Cancer Vaccine.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210452
Abstract: Cancer immunotherapies have reshaped the paradigm for cancer treatment over the past decade. Among them, therapeutic cancer vaccines that aim to modulate antigen presenting cells (e.g., dendritic cells (DCs)) and subsequent T cell priming processes… read more here.
Keywords: cancer vaccine; based situ; cancer vaccines; situ cancer ... See more keywords
Rethinking Antigen Source: Cancer Vaccines Based on Whole Tumor Cell/tissue Lysate or Whole Tumor Cell.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300121
Abstract: Cancer immunotherapies have improved human health, and one among the important technologies for cancer immunotherapy is cancer vaccine. Antigens are the most important components in cancer vaccines. Generally, antigens in cancer vaccines can be divided… read more here.
Keywords: cell; based whole; cancer vaccines; cancer ... See more keywords
Genetically modified cancer vaccines: Current status and future prospects.
Sign Up to like & getrecommendations! Published in 2022 at "Medicinal research reviews"
DOI: 10.1002/med.21882
Abstract: Vaccines can stimulate the immune system to protect individuals from infectious diseases. Moreover, vaccines have also been applied to the prevention and treatment of cancers. Due to advances in genetic engineering technology, cancer vaccines could… read more here.
Keywords: cancer; modified cancer; vaccines current; cancer vaccines ... See more keywords
mRNA Cancer Vaccines-Messages that Prevail.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in microbiology and immunology"
DOI: 10.1007/82_2017_509
Abstract: During the last decade, mRNA became increasingly recognized as a versatile tool for the development of new innovative therapeutics. Especially for vaccine development, mRNA is of outstanding interest and numerous clinical trials have been initiated.… read more here.
Keywords: mrna cancer; mrna vaccines; mrna; vaccines messages ... See more keywords
A New Generation of Vaccines in the Age of Immunotherapy
Sign Up to like & getrecommendations! Published in 2021 at "Current Oncology Reports"
DOI: 10.1007/s11912-021-01130-x
Abstract: Cancer vaccines are one of the most extensively studied immunotherapy type in solid tumors. Despite favorable presuppositions, so far, the use of cancer vaccines has been associated with disappointing results. However, a new generation of… read more here.
Keywords: new generation; vaccines age; cancer; generation vaccines ... See more keywords
Listeria monocytogenes Cancer Vaccines: Bridging Innate and Adaptive Immunity
Sign Up to like & getrecommendations! Published in 2019 at "Current Clinical Microbiology Reports"
DOI: 10.1007/s40588-019-00133-4
Abstract: Immunotherapy has emerged as a promising cancer treatment; however, success in only select clinical indications underscores the need for novel approaches. Recently Listeria monocytogenes–based vaccines have been developed to drive tumor-specific T cell responses. Here,… read more here.
Keywords: cell responses; cancer; innate adaptive; listeria monocytogenes ... See more keywords
Xenograft cancer vaccines prepared from immunodeficient mice increase tumor antigen diversity and host T cell efficiency against colorectal cancers.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.11.012
Abstract: Autologous cancer vaccines (ACVs) are a desirable approach for personalized medicine, but the efficiency of ACVs remains unsatisfactory due to their low immunogenicity. This study developed a platform that can enhance the immunogenicity of ACVs… read more here.
Keywords: cancer vaccines; ct26 scid; immunodeficient mice; cancer ... See more keywords
Turbocharging vaccines: emerging adjuvants for dendritic cell based therapeutic cancer vaccines.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in immunology"
DOI: 10.1016/j.coi.2017.06.003
Abstract: Development of therapeutic cancer vaccines has been hindered by the many pro-tumorigenic mechanisms at play in cancer patients that serve to suppress both antigen presenting cells and T cells. In face of these obstacles, cancer… read more here.
Keywords: vaccines emerging; turbocharging vaccines; emerging adjuvants; cancer ... See more keywords
Peptides as cancer vaccines.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2019.01.007
Abstract: Cancer vaccines based on synthetic peptides are a safe, well-tolerated immunotherapy able to specifically stimulate tumor-reactive T cells. However, their clinical efficacy does not approach that achieved with other immunotherapies such as immune checkpoint blockade.… read more here.
Keywords: cancer vaccines; peptides cancer; pharmacology; cancer ... See more keywords
Biomaterials for vaccine‐based cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.10.008
Abstract: &NA; The development of therapeutic cancer vaccines as a means to generate immune reactivity against tumors has been explored since the early discovery of tumor‐specific antigens by Georg Klein in the 1960s. However, challenges including… read more here.
Keywords: based cancer; vaccine based; biomaterials vaccine; cancer immunotherapy ... See more keywords
In silico analysis of transmembrane protein 31 (TMEM31) antigen to design novel multiepitope peptide and DNA cancer vaccines against melanoma.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular immunology"
DOI: 10.1016/j.molimm.2019.04.030
Abstract: Multiepitope cancer vaccines are announcing themselves as the future of melanoma treatment. Herein, high immunogenic regions of transmembrane protein 31 (TMEM31) antigen were selected according to cytotoxic T lymphocytes' (CTL) epitopes and major histocompatibility complex… read more here.
Keywords: tmem31 antigen; protein tmem31; multiepitope; cancer ... See more keywords