A Multifunctional Hydrogel Delivers Gold Compound and Inhibits Human Lung Cancer Xenograft
Sign Up to like & getrecommendations! Published in 2019 at "Pharmaceutical Research"
DOI: 10.1007/s11095-019-2581-z
Abstract: AbstractPurposeInterpenetrating network system (IPN), consisting of polyethylene glycol (PEG) –diacrylate (PEGdA) and modified gelatin, is a biocompatible and biodegradable hydrogel and has been studied for the local delivery of bioactive molecules and drugs. Gold(III) porphyrin(AuP)… read more here.
Keywords: hydrogel; cancer xenograft; human lung; lung cancer ... See more keywords
Design, synthesis and binding mode of interaction of novel small molecule o-hydroxy benzamides as HDAC3-selective inhibitors with promising antitumor effects in 4T1-Luc breast cancer xenograft model.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105446
Abstract: Histone deacetylase 3 (HDAC3) is one of the most promising targets to develop anticancer therapeutics. In continuation of our quest for selective HDAC3 inhibitors, a series of small molecules having o-hydroxy benzamide as the novel… read more here.
Keywords: 4t1 luc; cancer xenograft; luc breast; hdac3 selective ... See more keywords
Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-32094-x
Abstract: Human epidermal growth factor receptor 2 (HER2) overexpression occurs in various types of cancers. Regarding the anti-HER2 targeted therapies showed superior treatment outcomes in several (pre)clinical studies, we used multimodality image to rapidly select novel… read more here.
Keywords: gastric cancer; anti her2; cancer xenograft; her2 antibodies ... See more keywords
Assessment of Tumor Stiffness With Shear Wave Elastography in a Human Prostate Cancer Xenograft Implantation Model
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Ultrasound in Medicine"
DOI: 10.7863/ultra.16.03066
Abstract: To investigate the stiffness of human prostate cancer in a xenograft implantation model using shear wave elastography and compare the pathologic features of tumors with varying elasticity. read more here.
Keywords: implantation model; human prostate; xenograft implantation; shear wave ... See more keywords