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Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors

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1 Published in 2020 at "Science Advances"

DOI: 10.1126/sciadv.abc4517

Abstract: Growth of pancreatic cancers with hemizygous chromosomal 17p loss of MYBBP1A can be preferentially targeted by PARP inhibitors. Here, we selectively target pancreatic ductal adenocarcinoma (PDAC) cells harboring a hemizygous gene essential for cell growth.… read more here.

Keywords: mybbp1a; cancers hemizygous; pancreatic cancers; growth ... See more keywords