Articles with "cancers mechanisms" as a keyword



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Trabectedin in Cancers: Mechanisms and Clinical Applications.

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Published in 2022 at "Current pharmaceutical design"

DOI: 10.2174/1381612828666220526125806

Abstract: Trabectedin, a tetrahydroisoquinoline alkaloid, is the first marine antineoplastic agent approved with special anticancer mechanisms involving DNA binding, DNA repair pathways, transcription regulation and regulation of the tumor microenvironment. It has favorable clinical applications, especially… read more here.

Keywords: mechanisms clinical; trabectedin cancers; clinical applications; treatment ... See more keywords