GOF Mutant p53 in Cancers: A Therapeutic Challenge
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DOI: 10.3390/cancers14205091
Abstract: Simple Summary In normal cells, p53 is a protein which regulates the cell cycle progression to ensure normal cell division, growth, and development. However, in cancer, changes in the p53 DNA sequence, called genetic mutation,… read more here.
Keywords: cancers therapeutic; mutant p53; p53 cancers; p53 ... See more keywords
The Therapeutic Landscape for KRAS-Mutated Colorectal Cancers
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15082375
Abstract: Simple Summary More than a third of all colorectal cancers have a KRAS mutation. The complex biology of these cancers has challenged the development of direct targeting inhibitors. Substantial leaps have been made in recent… read more here.
Keywords: colorectal cancers; cancers therapeutic; development; mutated colorectal ... See more keywords