Refinement of computational identification of somatic copy number alterations using DNA methylation microarrays illustrated in cancers of unknown primary
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac161
Abstract: Abstract High-throughput genomic technologies are increasingly used in personalized cancer medicine. However, computational tools to maximize the use of scarce tissues combining distinct molecular layers are needed. Here we present a refined strategy, based on… read more here.
Keywords: methylation; number alterations; somatic copy; dna methylation ... See more keywords
Abstract 4209: Cancers of unknown primary: survival by histologic type, demographic features, and treatment in the US Military Health System
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4209
Abstract: Background: Cancers of unknown primary (CUP), a group of heterogenous metastatic cancers lacking a known primary site, have poor prognosis. This study compared survival by histologic type, patient characteristics, and treatment in the U.S. Military… read more here.
Keywords: unknown primary; survival; histologic type; cancers unknown ... See more keywords
Abstract 4534: National Multidisciplinary Tumor Board improves diagnostic stratification and therapeutic management in Cancers of Unknown Primary: the French Experience
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4534
Abstract: Introduction: With the increasing complexity of current diagnostic investigations, the integration of clinical, pathological and molecular characteristics is crucial for the management of patients (pts) with cancers of unknown primary (CUP). A national multidisciplinary tumor… read more here.
Keywords: multidisciplinary tumor; management; tumor board; cancers unknown ... See more keywords
Cancers of unknown primary diagnosed during hospitalization: a population-based study
Sign Up to like & getrecommendations! Published in 2017 at "BMC Cancer"
DOI: 10.1186/s12885-017-3083-1
Abstract: BackgroundCancers of Unknown Primary (CUP) are the 3-4th most common causes of cancer death and recent clinical guidelines recommend that patients should be directed to a team dedicated to their care. Our aim was to… read more here.
Keywords: medicine; admission; study; cancers unknown ... See more keywords
Utility of PET/CT in primary identification and management of cancers of unknown primary.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e18219
Abstract: e18219Background: The role of PET/CT in staging and management of cancers of unknown primary (CUP) is poorly defined. Our study sought to evaluate PET/CT versus standard CT in determining the prima... read more here.
Keywords: management cancers; cancers unknown; unknown primary; utility pet ... See more keywords
Mutated axon guidance gene PLXNB2 sustains growth and invasiveness of stem cells isolated from cancers of unknown primary
Sign Up to like & getrecommendations! Published in 2023 at "EMBO Molecular Medicine"
DOI: 10.15252/emmm.202216104
Abstract: The genetic changes sustaining the development of cancers of unknown primary (CUP) remain elusive. The whole‐exome genomic profiling of 14 rigorously selected CUP samples did not reveal specific recurring mutation in known driver genes. However,… read more here.
Keywords: cup; unknown primary; plxnb2; cancers unknown ... See more keywords