miR-33a inhibits cell proliferation and invasion by targeting CAND1 in lung cancer
Sign Up to like & getrecommendations! Published in 2017 at "Clinical and Translational Oncology"
DOI: 10.1007/s12094-017-1730-2
Abstract: BackgroundLung cancer continues to be one of the top five causes of cancer-related mortality. This study aims to identify down- and upregulated miRNAs and mRNA which can be used as potential biomarkers and/or therapeutic targets… read more here.
Keywords: proliferation; mir 33a; lung cancer; cancer ... See more keywords
Cullin-associated NEDD8-dissociated protein 1, a novel interactor of rabphilin-3A, deubiquitylates rabphilin-3A and regulates arginine vasopressin secretion in PC12 cells.
Sign Up to like & getrecommendations! Published in 2018 at "Endocrine journal"
DOI: 10.1507/endocrj.ej17-0399
Abstract: The molecular mechanism involved in the exocytosis of arginine vasopressin (AVP) is not fully known. Rabphilin-3A has been suggested as a novel autoantigen in infundibulo-neurohypophysitis (LINH), which leads to central diabetes insipidus through insufficient secretion… read more here.
Keywords: secretion; pc12 cells; rabphilin; arginine vasopressin ... See more keywords
CAND1 is required for pollen viability in Arabidopsis thaliana—a test of the adaptive exchange hypothesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.866086
Abstract: The dynamic assembly of SKP1•CUL1•F-box protein (SCF) ubiquitin ligases is important for protein ubiquitination and degradation. This process is enabled by CAND1, which exchanges F-box proteins associated with the common CUL1 scaffold, and thereby, recycles… read more here.
Keywords: exchange hypothesis; adaptive exchange; exchange; cand1 ... See more keywords
The Impact of Cand1 in Prostate Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12020428
Abstract: Evidence has accumulated asserting the importance of cullin-RING (really interesting new gene) ubiquitin ligases (CRLs) and their regulator Cullin-associated neural-precursor-cell-expressed developmentally down-regulated 8 (NEDD8) dissociated protein 1 (Cand1) in various cancer entities. However, the role… read more here.
Keywords: cand1 prostate; prostate cancer; cancer; cand1 ... See more keywords