Quorum sensing in Candida albicans: farnesol versus farnesoic acid
Sign Up to like & getrecommendations! Published in 2017 at "FEBS Letters"
DOI: 10.1002/1873-3468.12694
Abstract: Read the Original article at doi: 10.1002/1873-3468.12636. read more here.
Keywords: farnesol versus; sensing candida; quorum sensing; albicans farnesol ... See more keywords
A mathematical model captures the role of adenyl cyclase Cyr1 and guanidine exchange factor Ira2 in creating a growth‐to‐hyphal bistable switch in Candida albicans
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13470
Abstract: Recent biochemical experiments have indicated that in Candida albicans, a commensal fungal pathogen, the Ras signaling pathway plays a significant role in the yeast‐to‐hyphal transition; specifically, two enzymes in this pathway, Adenyl Cyclase Cyr1 and GTPase… read more here.
Keywords: bistable switch; adenyl cyclase; switch; cyclase cyr1 ... See more keywords
Photoinactivation of Catalase Sensitizes Candida albicans and Candida auris to ROS-Producing Agents and Immune Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced science"
DOI: 10.1002/advs.202104384
Abstract: Microbes have developed their own specific strategies to cope with reactive oxygen species (ROS). Catalase, a heme-containing tetramer expressed in a broad range of aerobic fungi, shows remarkable efficiency in degrading hydrogen peroxide (H2 O2 ) for… read more here.
Keywords: photoinactivation catalase; candida auris; photoinactivation; catalase ... See more keywords
Sequence Variation of Candida albicans Sap2 Enhances Fungal Pathogenicity via Complement Evasion and Macrophage M2-Like Phenotype Induction.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202206713
Abstract: Candida albicans (C. albicans) is an opportunistic pathogen increasingly causing candidiasis worldwide. This study aims to investigate the pattern of systemic immune responses triggered by C. albicans with disease associated variation of Sap2, identifying the… read more here.
Keywords: evasion; variation; pathogenicity; sequence variation ... See more keywords
Potential role of potassium and chloride channels in regulation of silymarin‐induced apoptosis in Candida albicans
Sign Up to like & getrecommendations! Published in 2018 at "IUBMB Life"
DOI: 10.1002/iub.1716
Abstract: Silymarin, which is derived from the seeds of Silybum marianum, has been widely used to prevent and treat liver diseases. In our previous study, we reported that at concentrations above the minimal inhibitory concentration (MIC),… read more here.
Keywords: potassium; silymarin; concentration mic; candida albicans ... See more keywords
Target-based drug repurposing against Candida albicans-A computational modeling, docking, and molecular dynamic simulations study.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30163
Abstract: The emergence of multidrug-resistant strains of Candida albicans has become a global threat mostly due to co-infection with immune-compromised patients leading to invasive candidiasis. The life-threatening form of the disease can be managed quickly and… read more here.
Keywords: drug repurposing; dynamic simulations; target; drug ... See more keywords
Toward more potent imidazopyridine inhibitors of Candida albicans Bdf1: Modeling the role of structural waters in selective ligand binding
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Computational Chemistry"
DOI: 10.1002/jcc.26997
Abstract: Novel agents to treat invasive fungal infections are urgently needed because the small number of established targets in pathogenic fungi makes the existing drug repertoire particularly vulnerable to the emergence of resistant strains. Recently, we… read more here.
Keywords: toward potent; albicans bdf1; ligand; potent imidazopyridine ... See more keywords
Phenotype, genotype, and mating type determination in oral Candida albicans isolates from pediatric patients with neutropenia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24664
Abstract: The most frequent species of Candida to infect and colonize patients with neutropenia is still Candida albicans. This study aimed to provide detailed information on the phenotype, genotype, and mating type of oral C. albicans… read more here.
Keywords: mating type; phenotype genotype; patients neutropenia; genotype mating ... See more keywords
Antimicrobial activity of intracanal medications against both Enterococcus faecalis and Candida albicans biofilm
Sign Up to like & getrecommendations! Published in 2019 at "Microscopy Research and Technique"
DOI: 10.1002/jemt.23192
Abstract: Enterococcus faecalis and Candida albicans have been associated with cases of secondary and persistent root canal infections, been resistant to calcium hydroxide. So, the evaluation of the susceptibility of these microorganisms biofilms to new drugs… read more here.
Keywords: microscopy; enterococcus faecalis; candida albicans; calcium hydroxide ... See more keywords
Assessing pH‐dependent activities of virulence factors secreted by Candida albicans
Sign Up to like & getrecommendations! Published in 2023 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.1342
Abstract: Candida albicans is an opportunistic pathogen that can thrive under adverse conditions including suboptimal pH, nutrient scarcity, and low levels of oxygen. Its pathogenicity is associated with the production of virulence factors such as extracellular… read more here.
Keywords: activities virulence; dependent activities; assessing dependent; virulence ... See more keywords
SILAC Expands its Territory to the Pathogenic Yeast, Candida albicans
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700458
Abstract: Quantitative proteomic analysis using stable isotope labeling with amino acids in cell culture (SILAC), as metabolic labeling with MS, has been used as an excellent technique to measure relative abundance change in proteins and post‐transitional… read more here.
Keywords: pathogenic yeast; candida albicans; silac expands; expands territory ... See more keywords