Evolution of drug resistance in an antifungal-naive chronic Candida lusitaniae infection
Sign Up to like & getrecommendations! Published in 2018 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1807698115
Abstract: Significance Drug-resistant subpopulations of microbes or tumor cells are difficult to detect but can confound disease treatment. In this deep characterization of a chronic fungal infection, we report unprecedented heterogeneity in the drug resistance-related gene… read more here.
Keywords: drug resistance; infection; drug; drug resistant ... See more keywords
A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts
Sign Up to like & getrecommendations! Published in 2017 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.01483-17
Abstract: ABSTRACT A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically modified for use as a cellular model for assessing by allele replacement the impact of lanosterol C14α-demethylase ERG11 mutations on azole resistance. Candida… read more here.
Keywords: ctg clade; candida; resistance; yeast ... See more keywords
Candida lusitaniae: Biology, Pathogenicity, Virulence Factors, Diagnosis, and Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s383785
Abstract: Abstract The incidence of fungal infections is increasing at an alarming rate and has posed a great challenge for science in recent years. The rise in these infections has been related to the increase in… read more here.
Keywords: diagnosis treatment; candida lusitaniae; biology; virulence factors ... See more keywords
Mediator Subunit Med15 Regulates Cell Morphology and Mating in Candida lusitaniae
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Fungi"
DOI: 10.3390/jof9030333
Abstract: Candida lusitaniae is an emerging opportunistic pathogenic yeast capable of shifting from yeast to pseudohyphae form, and it is one of the few Candida species with the ability to reproduce sexually. In this study, we… read more here.
Keywords: mediator subunit; candida lusitaniae; med15; cell separation ... See more keywords