Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes
Sign Up to like & getrecommendations! Published in 2021 at "genesis"
DOI: 10.1002/dvg.23414
Abstract: Cilia are present on most vertebrate cells and play a central role in development, growth, and homeostasis. Thus, cilia dysfunction can manifest into an array of diseases, collectively termed ciliopathies, affecting millions of lives worldwide.… read more here.
Keywords: candidate ciliopathy; xenopus rescue; rescue model; candidate ... See more keywords
A rare FGF5 candidate variant (rs112475347) for predisposition to nonsquamous, nonsmall‐cell lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Cancer"
DOI: 10.1002/ijc.34510
Abstract: A unique approach with rare resources was used to identify candidate variants predisposing to familial nonsquamous nonsmall‐cell lung cancers (NSNSCLC). We analyzed sequence data from NSNSCLC‐affected cousin pairs belonging to high‐risk lung cancer pedigrees identified… read more here.
Keywords: lung cancer; predisposition; variant; cancer ... See more keywords
Nutrition and the transplant candidate
Sign Up to like & getrecommendations! Published in 2017 at "Liver Transplantation"
DOI: 10.1002/lt.24848
Abstract: Cirrhosis is the most common indication for liver transplantation (LT) worldwide. Malnutrition is present in at least two‐thirds of patients with cirrhosis awaiting LT. It negatively impacts survival, quality of life, and the ability to… read more here.
Keywords: malnutrition cirrhosis; malnutrition; candidate; cirrhosis ... See more keywords
Packing returning secretaries
Sign Up to like & getrecommendations! Published in 2021 at "Networks"
DOI: 10.1002/net.22000
Abstract: We study online secretary problems with returns in combinatorial packing domains with n candidates that arrive sequentially over time in random order. The goal is to determine a feasible packing of candidates of maximum total… read more here.
Keywords: returning secretaries; log; packing returning; candidate ... See more keywords
Plasmonic Nanoassemblies: Tentacles Beat Satellites for Boosting Broadband NIR Plasmon Coupling Providing a Novel Candidate for SERS and Photothermal Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201906780
Abstract: Optical theranostic applications demand near-infrared (NIR) localized surface plasmon resonance (LSPR) and maximized electric field at nanosurfaces and nanojunctions, aiding diagnosis via Raman or optoacoustic imaging, and photothermal-based therapies. To this end, multiple permutations and… read more here.
Keywords: candidate; nanoassemblies tentacles; broadband; plasmon ... See more keywords
Candidate diagnostic biomarkers for neurodevelopmental disorders in children and adolescents: a systematic review
Sign Up to like & getrecommendations! Published in 2023 at "World Psychiatry"
DOI: 10.1002/wps.21037
Abstract: Neurodevelopmental disorders – including attention‐deficit/hyperactivity disorder (ADHD), autism spectrum disorder, communication disorders, intellectual disability, motor disorders, specific learning disorders, and tic disorders – manifest themselves early in development. Valid, reliable and broadly usable biomarkers supporting… read more here.
Keywords: neurodevelopmental disorders; candidate diagnostic; disorders children; systematic review ... See more keywords
Molecular Characterization of a Vector-Based Candidate Antigen Using the 3'-RACE and Genome Walking Methods and In Silico Analysis of the Correspondent Protein for Vaccine Design and Development.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1884-4_29
Abstract: The main objectives of developing vaccines to prevent malaria transmission are malaria control and preventing the reemergence of the disease in endemic regions. Molecular and in silico characterization of a candidate molecule is the first… read more here.
Keywords: characterization; genome walking; vaccine design; race genome ... See more keywords
Fine mapping and candidate gene analysis of qhkw5-3, a major QTL for kernel weight in maize
Sign Up to like & getrecommendations! Published in 2019 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-019-03372-7
Abstract: Key messageqhkw5-3, a major QTL for kernel weight in maize, was mapped to an interval of 125.3 kb between the InDel markers InYM20 and InYM36, and the candidate genes were analysed.AbstractYield, of which kernel weight is… read more here.
Keywords: qhkw5; candidate; qtl kernel; kernel weight ... See more keywords
Identification of Novel Congenital Heart Disease Candidate Genes Using Chromosome Microarray
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Cardiology"
DOI: 10.1007/s00246-017-1741-3
Abstract: While the majority of patients have isolated heart disease, congenital heart disease (CHD) may be associated with other congenital anomalies or syndromes. Our institution utilizes chromosomal microarray (CMA) to identify chromosomal abnormalities, specifically copy number… read more here.
Keywords: heart disease; candidate; candidate genes; cnvs ... See more keywords
Integrative analysis of transcriptome-wide association study data and mRNA expression profiles identified candidate genes and pathways associated with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01418-w
Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia characterized by extensive structural, contractile and electrophysiological remodeling. The genetic basis of AF remained elusive until now. Transcriptome-wide association study (TWAS) was conducted by FUSION… read more here.
Keywords: candidate; expression; candidate genes; association study ... See more keywords
A Novel Multiplex Based Platform for Osteoarthritis Drug Candidate Evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Biomedical Engineering"
DOI: 10.1007/s10439-020-02539-4
Abstract: Osteoarthritis (OA) is characterized by irreversible cartilage degradation with very limited therapeutic interventions. Drug candidates targeted at prototypic players had limited success until now and systems based approaches might be necessary. Consequently, drug evaluation platforms… read more here.
Keywords: drug; evaluation; candidate; cartilage degradation ... See more keywords