Reply to “Serum Neurofilaments as Candidate Biomarkers of Natalizumab Progressive Multifocal Leukoencephalopathy”
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Neurology"
DOI: 10.1002/ana.25526
Abstract: In our recently published study we found that at the onset of PML serum NfL were 10-fold higher than in the pre-PML condition and in natalizumab-treated or untreated MS patients. The findings by Loonstra et… read more here.
Keywords: reply serum; biomarkers natalizumab; serum neurofilaments; candidate biomarkers ... See more keywords
Candidate biomarkers in psychiatric disorders: state of the field
Sign Up to like & getrecommendations! Published in 2023 at "World Psychiatry"
DOI: 10.1002/wps.21078
Abstract: The field of psychiatry is hampered by a lack of robust, reliable and valid biomarkers that can aid in objectively diagnosing patients and providing individualized treatment recommendations. Here we review and critically evaluate the evidence… read more here.
Keywords: biomarkers psychiatric; state; treatment; candidate biomarkers ... See more keywords
IDENTIFICATION AND ASSESSMENT OF CANDIDATE BIOMARKERS IN EARLY DETECTION AND PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.03.141
Abstract: Background An integrated approach for understanding molecular transformation of OSCC, facilitating early detection of invasion and metastasis is sustainable. The workflow, including bioinformatics to predict candidate genes, confirming their presence with proteomics and validation of… read more here.
Keywords: candidate; progression; candidate biomarkers; early detection ... See more keywords
Assessment of candidate biomarkers to detect resistance to Mycobacterium bovis in Holstein-Friesian cattle.
Sign Up to like & getrecommendations! Published in 2020 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2020.07.016
Abstract: Bovine tuberculosis (bTB) caused by Mycobacterium bovis has a significant economic impact worldwide each year. Control of bTB is based on skin testing and removal of reactors. However, additional strategies are required to control this… read more here.
Keywords: mycobacterium bovis; candidate biomarkers; resistance;
Internal Standard Triggered-Parallel Reaction Monitoring Mass Spectrometry Enables Multiplexed Quantification of Candidate Biomarkers in Plasma
Sign Up to like & getrecommendations! Published in 2022 at "Analytical Chemistry"
DOI: 10.1021/acs.analchem.1c04382
Abstract: Despite advances in proteomic technologies, clinical translation of plasma biomarkers remains low, partly due to a major bottleneck between the discovery of candidate biomarkers and costly clinical validation studies. Due to a dearth of multiplexable… read more here.
Keywords: triggered parallel; mass spectrometry; internal standard; standard triggered ... See more keywords
Candidate biomarkers of physical frailty in heart failure: an exploratory cross-sectional study.
Sign Up to like & getrecommendations! Published in 2022 at "European journal of cardiovascular nursing"
DOI: 10.1093/eurjcn/zvac054
Abstract: AIMS Physical frailty is highly prevalent and predictive of worse outcomes in heart failure (HF). Candidate biomarker analysis may help in understanding the mechanisms underlying physical frailty in HF. We aimed to identify candidate biomarkers… read more here.
Keywords: physical frailty; candidate biomarkers; heart failure; frailty ... See more keywords
Candidate Biomarkers for Sepsis-Associated Acute Kidney Injury Mechanistic Studies
Sign Up to like & getrecommendations! Published in 2022 at "SHOCK"
DOI: 10.1097/shk.0000000000001916
Abstract: ABSTRACT Introduction: Sepsis-associated acute kidney injury (SA-AKI) is a frequent complication of sepsis, yet the pathophysiologic mechanisms of SA-AKI are incompletely understood. PERSEVERE is a clinically validated serum biomarker panel with high sensitivity in predicting… read more here.
Keywords: aki; kidney; mice; sepsis associated ... See more keywords
Candidate Biomarkers and Molecular Mechanism Investigation for Glioblastoma Multiforme Utilizing WGCNA
Sign Up to like & getrecommendations! Published in 2018 at "BioMed Research International"
DOI: 10.1155/2018/4246703
Abstract: To reveal the potential molecular mechanism of glioblastoma multiforme (GBM) and provide the candidate biomarkers for GBM gene therapy. Microarray dataset GSE50161 was obtained from GEO database. The differentially expressed genes (DEGs) were identified between… read more here.
Keywords: candidate biomarkers; molecular mechanism; glioblastoma multiforme;
Bioinformatics Identification of Candidate Biomarkers in Endomyocardial Biopsy and Peripheral Blood for Cardiac Allograft Rejection
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Transplantation"
DOI: 10.12659/aot.935488
Abstract: Background Cardiac allograft rejection is still a crucial barrier to achieving satisfactory outcomes after surgery. In this study, we propose to find candidate biomarkers from endomyocardial biopsy (EMB) and peripheral blood (PB) samples for efficient… read more here.
Keywords: emb samples; cardiac allograft; allograft rejection; candidate biomarkers ... See more keywords
Identifying Exosome-Derived MicroRNAs as Candidate Biomarkers of Frailty
Sign Up to like & getrecommendations! Published in 2017 at "The Journal of Frailty & Aging"
DOI: 10.14283/jfa.2017.45
Abstract: Frailty is a geriatric syndrome associated with progressive physical decline and significantly increases risk for falls, disability, hospitalizations, and death. However, much remains unknown regarding the biological mechanisms that contribute to aging and frailty, and… read more here.
Keywords: biomarkers frailty; mir; derived micrornas; candidate biomarkers ... See more keywords
Heat Shock Proteins: Potential Modulators and Candidate Biomarkers of Peripartum Cardiomyopathy
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2021.633013
Abstract: Peripartum cardiomyopathy (PPCM) is a potentially life-threatening condition in which heart failure and systolic dysfunction occur late in pregnancy or within months following delivery. To date, no reliable biomarkers or therapeutic interventions for the condition… read more here.
Keywords: heat shock; shock proteins; candidate biomarkers; peripartum cardiomyopathy ... See more keywords