HSF1 Pathway Inhibitor Clinical Candidate (CCT361814/NXP800) Developed from a Phenotypic Screen as a Potential Treatment for Refractory Ovarian Cancer and Other Malignancies
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DOI: 10.1021/acs.jmedchem.3c00156
Abstract: CCT251236 1, a potent chemical probe, was previously developed from a cell-based phenotypic high-throughput screen (HTS) to discover inhibitors of transcription mediated by HSF1, a transcription factor that supports malignancy. Owing to its activity against… read more here.
Keywords: cct361814 nxp800; clinical candidate; treatment refractory; candidate cct361814 ... See more keywords