Articles with "candidate drug" as a keyword



Evaluation of the mosquitocidal efficacy of fluralaner, a potential candidate for drug based vector control

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-56053-x

Abstract: Vector control is a key intervention against mosquito borne diseases. However, conventional methods have several limitations and alternate strategies are in urgent need. Vector control with endectocides such as ivermectin is emerging as a novel… read more here.

Keywords: vector; vector control; efficacy fluralaner; candidate drug ... See more keywords

MP77-04 H-IPSE, A PARASITE-DERIVED CANDIDATE DRUG FOR BLADDER PAIN, IS INTERNALIZED THROUGH CLATHRIN- AND CAVEOLIN-MEDIATED UPTAKE AND LOCALIZES WITHIN NON-UROTHELIAL CELLS

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Published in 2020 at "Journal of Urology"

DOI: 10.1097/ju.0000000000000963.04

Abstract: distinct focal inflammatory areas in the bladder mucosa observed in a minority of patients diagnosed with IC/BPS. This is the first comprehensive evaluation of the microbiome of HL patients using a casecontrol design in an… read more here.

Keywords: candidate drug; male; ipse parasite; derived candidate ... See more keywords

Promoting Angiogenesis Effect and Molecular Mechanism of Isopropyl Caffeate (KYZ), a Novel Metabolism-Derived Candidate Drug, Based on Integrated Network Pharmacology and Transgenic Zebrafish Models

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2022.901460

Abstract: Aim of the study: Ischemic diseases have a huge impact on people’s health, which can cause blood supply blockage or restriction in specific tissues. Researchers must develop novel drugs with great efficacy and low toxicity… read more here.

Keywords: candidate drug; pharmacology; angiogenesis; network pharmacology ... See more keywords
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Jasminum sambac: A Potential Candidate for Drug Development to Cure Cardiovascular Ailments

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Published in 2021 at "Molecules"

DOI: 10.3390/molecules26185664

Abstract: Jasminum sambac (L.) is a South Asian folkloric medicinal plant that has traditionally been used to treat cardiovascular problems. The current investigation was meticulously organized to explore the pharmacological foundation for the medicinal uses of… read more here.

Keywords: sambac potential; drug development; cardiovascular ailments; jasminum sambac ... See more keywords

Flunarizine as a Candidate for Drug Repurposing Against Human Pathogenic Mammarenaviruses

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Published in 2025 at "Viruses"

DOI: 10.3390/v17010117

Abstract: Lassa fever (LF), a viral hemorrhagic fever disease with a case fatality rate that can be over 20% among hospitalized LF patients, is endemic to many West African countries. Currently, no vaccines or therapies are… read more here.

Keywords: drug repurposing; repurposing human; candidate drug; flunarizine candidate ... See more keywords