The clinical relevance of multiple DPYD polymorphisms on patients candidate for fluoropyrimidine based-chemotherapy. An Italian case-control study
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DOI: 10.1038/s41416-019-0423-8
Abstract: BackgroundDeleterious polymorphisms in the gene encoding DPD (DPYD) may result in severe reduction of DPD enzymatic activity that causes life-threatening toxicities when the standard dose of fluorouracil is used. The best panel of single-nucleotide polymorphism… read more here.
Keywords: dpyd; candidate fluoropyrimidine; fluoropyrimidine; fluoropyrimidine based ... See more keywords