Candidate genes involved in metastasis of colon cancer identified by integrated analysis
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2071
Abstract: Colon cancer is one of the most malignant cancers worldwide. Nearly 20% of all colon cancer patients are diagnosed at stage IV (metastasis). However, further study of colon cancer is difficult due to a lack… read more here.
Keywords: analysis; metastasis; colon cancer; candidate genes ... See more keywords
Screening of potential novel candidate genes in schwannomatosis patients
Sign Up to like & getrecommendations! Published in 2022 at "Human Mutation"
DOI: 10.1002/humu.24424
Abstract: Schwannomatosis comprises a group of hereditary tumor predisposition syndromes characterized by, usually benign, multiple nerve sheath tumors, which frequently cause severe pain that does not typically respond to drug treatments. The most common schwannomatosis‐associated gene… read more here.
Keywords: genes schwannomatosis; candidate genes; screening potential; schwannomatosis patients ... See more keywords
Lrp5 Mutant and Crispant Zebrafish Faithfully Model Human Osteoporosis, Establishing the Zebrafish as a Platform for CRISPR‐Based Functional Screening of Osteoporosis Candidate Genes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4327
Abstract: Genomewide association studies (GWAS) have improved our understanding of the genetic architecture of common complex diseases such as osteoporosis. Nevertheless, to attribute functional skeletal contributions of candidate genes to osteoporosis‐related traits, there is a need… read more here.
Keywords: crispr based; osteoporosis candidate; candidate genes; osteoporosis ... See more keywords
Functional genomics of reproduction in pigs: Are we there yet?
Sign Up to like & getrecommendations! Published in 2022 at "Molecular reproduction and development"
DOI: 10.1002/mrd.23625
Abstract: Reproductive failure is the main reason for culling females in swine herds and is both a financial and sustainability issue. Because reproductive traits are complex and lowly to moderately heritable, genomic selection within populations can… read more here.
Keywords: reproduction pigs; candidate genes; genomics reproduction; pigs yet ... See more keywords
Integrative Functional Genomics for Systems Genetics in GeneWeaver.org.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6427-7_6
Abstract: The abundance of existing functional genomics studies permits an integrative approach to interpreting and resolving the results of diverse systems genetics studies. However, a major challenge lies in assembling and harmonizing heterogeneous data sets across… read more here.
Keywords: geneweaver org; integrative functional; genetics; functional genomics ... See more keywords
A genome-wide association study uncovers novel genomic regions and candidate genes of yield-related traits in upland cotton
Sign Up to like & getrecommendations! Published in 2018 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-018-3162-y
Abstract: Key messageA total of 62 SNPs associated with yield-related traits were identified by a GWAS. Based on significant SNPs, two candidate genes pleiotropically increase lint yield.AbstractImproved fibre yield is considered a constant goal of upland… read more here.
Keywords: related traits; yield related; candidate genes; upland cotton ... See more keywords
Identification of Novel Congenital Heart Disease Candidate Genes Using Chromosome Microarray
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Cardiology"
DOI: 10.1007/s00246-017-1741-3
Abstract: While the majority of patients have isolated heart disease, congenital heart disease (CHD) may be associated with other congenital anomalies or syndromes. Our institution utilizes chromosomal microarray (CMA) to identify chromosomal abnormalities, specifically copy number… read more here.
Keywords: heart disease; candidate; candidate genes; cnvs ... See more keywords
Integrative analysis of transcriptome-wide association study data and mRNA expression profiles identified candidate genes and pathways associated with atrial fibrillation
Sign Up to like & getrecommendations! Published in 2019 at "Heart and Vessels"
DOI: 10.1007/s00380-019-01418-w
Abstract: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia characterized by extensive structural, contractile and electrophysiological remodeling. The genetic basis of AF remained elusive until now. Transcriptome-wide association study (TWAS) was conducted by FUSION… read more here.
Keywords: candidate; expression; candidate genes; association study ... See more keywords
Transcriptional profiling of wheat and wheat-rye addition lines to identify candidate genes for aluminum tolerance
Sign Up to like & getrecommendations! Published in 2018 at "Biologia Plantarum"
DOI: 10.1007/s10535-018-0804-5
Abstract: A large-scale expression profiling study was performed to investigate candidate genes associated with the two quantitative trait loci for aluminum (Al) tolerance (Alt1 and Alt2). They have been identified in rye and localized on chromosomes… read more here.
Keywords: line; tolerance; wheat; candidate genes ... See more keywords
Unmapped sequencing reads identify additional candidate genes linked to magnetoreception in rainbow trout
Sign Up to like & getrecommendations! Published in 2018 at "Environmental Biology of Fishes"
DOI: 10.1007/s10641-018-0731-5
Abstract: A recent study identified candidate genes linked to magnetoreception in rainbow trout (Oncorhynchus mykiss) by sequencing transcriptomes from the brains of fish exposed to a magnetic pulse. However, the discovery of these candidate genes was… read more here.
Keywords: magnetoreception rainbow; genes linked; candidate; linked magnetoreception ... See more keywords
Meta-QTL analysis and identification of candidate genes related to root traits in maize
Sign Up to like & getrecommendations! Published in 2018 at "Euphytica"
DOI: 10.1007/s10681-018-2283-3
Abstract: Maize root system architecture determines key functions of uptake of water and nutrients in plants. A large number of quantitative trait loci (QTLs) of root-related traits have been found in different populations of maize. Identification… read more here.
Keywords: root traits; related root; root; identification candidate ... See more keywords