Articles with "candidate pharmacogenetic" as a keyword



The role of candidate pharmacogenetic variants in determining valproic acid efficacy, toxicity and concentrations in patients with epilepsy

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Published in 2024 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2024.1483723

Abstract: Background Antiseizure medications (ASM) exhibit considerable interindividual variability in terms of efficacy and adverse events. Genetic variation is thought to contribute to these differences in clinical outcomes. Specifically, the response to valproic acid (VPA), a… read more here.

Keywords: pharmacogenetic variants; treatment; candidate pharmacogenetic; efficacy ... See more keywords