Atorvastatin preferentially inhibits the growth of high ZEB-expressing canine cancer cells.
Sign Up to like & getrecommendations! Published in 2021 at "Veterinary and comparative oncology"
DOI: 10.1111/vco.12778
Abstract: The epithelial-to-mesenchymal transition (EMT) is fundamental in cancer progression and contributes to the acquisition of malignant properties. The statin class of cholesterol-lowering drugs exhibits pleiotropic anticancer effects in vitro and in vivo, and many epidemiologic… read more here.
Keywords: zeb; sensitivity; cancer cells; cancer ... See more keywords
Review: NF-kB activation in canine cancer
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Pathology"
DOI: 10.1177/03009858221092017
Abstract: Spontaneous tumors in dogs share several environmental, epidemiologic, biologic, clinical and molecular features with a wide variety of human cancers, making this companion animal an attractive model. Nuclear factor kappa B (NF-kB) transcription factor overactivation… read more here.
Keywords: canine cancer; cancer review; canine; human cancers ... See more keywords
Establishment and Initial Experience of Clinical FLASH Radiotherapy in Canine Cancer Patients
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.658004
Abstract: FLASH radiotherapy has emerged as a treatment technique with great potential to increase the differential effect between normal tissue toxicity and tumor response compared to conventional radiotherapy. To evaluate the feasibility of FLASH radiotherapy in… read more here.
Keywords: canine cancer; cancer patients; radiotherapy; flash radiotherapy ... See more keywords