G2/M arrest and mitotic slippage induced by fenbendazole in canine melanoma cells
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DOI: 10.1002/vms3.733
Abstract: Abstract Background The use of fenbendazole (FBZ) in terminal cancer patients has recently increased, as anthelminthic drugs, such as FBZ and benzimidazole, exhibit anti‐tubulin effects in tumour cells. Objectives The present study evaluated the in… read more here.
Keywords: mitotic slippage; cell; canine melanoma; melanoma ... See more keywords
Evaluation of galectins 1 and 3 expression in canine melanoma
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DOI: 10.1590/1678-5150-pvb-6377
Abstract: ABSTRACT: Canine melanoma is a frequently-occuring neoplasm in dogs and presents as malignant and highly metastatic in this context, studies that contribute to the understanding of the tumor microenvironment in melanoma include the role of… read more here.
Keywords: galectin galectin; galectins expression; canine melanoma; melanoma ... See more keywords
Effects of Cyclooxygenase-2 in Canine Melanoma-derived Extracellular Vesicles on Tumor Microenvironment In Vitro
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DOI: 10.21873/anticanres.16044
Abstract: Abstract Background/Aim: Tumor cell-derived extracellular vesicles (TEVs) promote tumor growth and metastasis; thus, they have drawn the attention of researchers. TEVs regulate the tumor microenvironment by facilitating crosstalk between immune and stromal cells. Macrophages are… read more here.
Keywords: canine melanoma; melanoma; derived extracellular; melanoma derived ... See more keywords
Use of a canine melanoma vaccine in the management of malignant melanoma in an African penguin (Spheniscus demersus).
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Veterinary Medical Association"
DOI: 10.2460/javma.20.10.0564
Abstract: CASE DESCRIPTION A 25-year-old 4.4-kg male aquarium-hatched African penguin (Spheniscus demersus) was evaluated because of a raised 1.5 × 0.5-cm pigmented mass extending from within the right naris noted 2 days earlier. CLINICAL FINDINGS The… read more here.
Keywords: canine melanoma; melanoma; penguin; melanoma vaccine ... See more keywords
Current Status of Canine Melanoma Diagnosis and Therapy: Report From a Colloquium on Canine Melanoma Organized by ABROVET (Brazilian Association of Veterinary Oncology)
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.707025
Abstract: Citation: Fonseca-Alves CE, Ferreira Ê, de Oliveira Massoco C, Strauss BE, Fávaro WJ, Durán N, Oyafuso da Cruz N, dos Santos Cunha SC, Castro JLC, Rangel MMM, Brunner CHM, Tellado M, dos Anjos DS, Fernandes… read more here.
Keywords: oncology; canine melanoma; current status; status canine ... See more keywords
Canine melanoma: A review of diagnostics and comparative mechanisms of disease and immunotolerance in the era of the immunotherapies
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.1046636
Abstract: Melanomas in humans and dogs are highly malignant and resistant to therapy. Since the first development of immunotherapies, interest in how the immune system interacts within the tumor microenvironment and plays a role in tumor… read more here.
Keywords: immunotolerance; canine melanoma; development; comparative mechanisms ... See more keywords
Canine Melanoma Immunology and Immunotherapy: Relevance of Translational Research
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.803093
Abstract: In veterinary oncology, canine melanoma is still a fatal disease for which innovative and long-lasting curative treatments are urgently required. Considering the similarities between canine and human melanoma and the clinical revolution that immunotherapy has… read more here.
Keywords: oncology; canine melanoma; melanoma; immunotherapy ... See more keywords