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Published in 2019 at "Human Genetics"
DOI: 10.1007/s00439-019-01976-z
Abstract: Therapies for Duchenne muscular dystrophy (DMD) must first be tested in animal models to determine proof-of-concept, efficacy, and importantly, safety. The murine and canine models for DMD are genetically homologous and most commonly used in…
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Keywords:
canine models;
therapies canine;
muscular dystrophy;
gene ... See more keywords
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Published in 2019 at "Human Genetics"
DOI: 10.1007/s00439-019-01997-8
Abstract: Amelogenesis imperfecta (AI) refers to a genetically and clinically heterogeneous group of inherited disorders affecting the structure, composition, and quantity of tooth enamel. Both non-syndromic and syndromic forms of AI have been described and several…
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Keywords:
canine models;
amelogenesis imperfecta;
enam;
novel recessive ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0177224
Abstract: We have analyzed the complex pattern of the inflammatory response in early-onset canine models of human retinitis pigmentosa, rcd1, xlpra2 and erd, as well as late-onset xlpra1, in comparative manner. The time course of immune…
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Keywords:
canine models;
early onset;
response;
inflammatory genes ... See more keywords
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Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.876178
Abstract: Pulmonary hypertension (PH) is a life-threatening disease in dogs characterized by increased pulmonary arterial pressure (PAP) and/or pulmonary vascular resistance. No study has evaluated the utility of Beraprost sodium (BPS) in dogs with PH. This…
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Keywords:
beraprost sodium;
pulmonary hypertension;
hemodynamics;
bps ... See more keywords