Canine reference genome accuracy impacts variant calling: Lessons learned from investigating embryonic lethal variants.
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DOI: 10.1111/age.13241
Abstract: Deficient homozygosity of a variant maintained in a population suggests that the variant may be embryonic lethal. We examined whole genome sequence data from 675 canids to investigate for variants with missing homozygosity and high… read more here.
Keywords: reference; reference genome; genome; embryonic lethal ... See more keywords