Critical Illness Secondary to Synthetic Cannabinoid Ingestion
Sign Up to like & getrecommendations! Published in 2020 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2020.8516
Abstract: Key Points Question What are the clinical manifestations of synthetic cannabinoid intoxication, and are they life threatening? Findings This case series of 30 adult patients describes the acute neurologic and cardiopulmonary complications of synthetic cannabinoid… read more here.
Keywords: critical illness; illness secondary; synthetic cannabinoid; cannabinoid ... See more keywords
Identification of the synthetic cannabinoid‐type new psychoactive substance, CH‐PIACA, in seized material
Sign Up to like & getrecommendations! Published in 2022 at "Drug Testing and Analysis"
DOI: 10.1002/dta.3333
Abstract: Abstract Synthetic cannabinoids (SCs) remain the largest class of new psychoactive substances (NPS), and while the number of NPS that are reported to the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) for the… read more here.
Keywords: seized material; piaca; new psychoactive; cannabinoid ... See more keywords
Astroglial cannabinoid signaling and behavior
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24171
Abstract: In neuroscience, the explosion of innovative and advanced technical accomplishments is fundamental to understanding brain functioning. For example, the possibility to distinguish glial and neuronal activities at the synaptic level and/or the appearance of new… read more here.
Keywords: cannabinoid receptors; cannabinoid; cannabinoid signaling; signaling behavior ... See more keywords
Molecular networks underlying cannabinoid signaling in skeletal muscle plasticity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30837
Abstract: The cannabinoid system is ubiquitously present and is classically considered to engage in neural and immunity processes. Yet, the role of the cannabinoid system in the whole body and tissue metabolism via central and peripheral… read more here.
Keywords: metabolism; cannabinoid system; muscle; cannabinoid ... See more keywords
Cannabinoid Receptors in Regulating the GI Tract: Experimental Evidence and Therapeutic Relevance.
Sign Up to like & getrecommendations! Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_105
Abstract: Cannabinoid receptors are fundamentally involved in all aspects of intestinal physiology, such as motility, secretion, and epithelial barrier function. They are part of a broader entity, the so-called endocannabinoid system which also includes their endocannabinoid… read more here.
Keywords: tract experimental; cannabinoid receptors; regulating tract; experimental evidence ... See more keywords
Cannabinoid Signaling in Glioma Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-30651-9_11
Abstract: Cannabinoids are a group of structurally heterogeneous but pharmacologically related compounds, including plant-derived cannabinoids, synthetic substances and endogenous cannabinoids, such as anandamide and 2-arachidonoylglycerol. Cannabinoids elicit a wide range of central and peripheral effects mostly… read more here.
Keywords: signaling glioma; cannabinoid; glioma cells; cannabinoid signaling ... See more keywords
Cisplatin-induced ototoxicity involves interaction of PRMT3 and cannabinoid system
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Toxicology"
DOI: 10.1007/s00204-019-02507-5
Abstract: This study investigated whether protein arginine methyltransferase (PRMT) and the cannabinoid system are involved in cisplatin-induced ototoxicity. Cisplatin increased cytosine–cytosine–adenosine–adenosine–thymidine–enhancer-binding protein homologous protein expression. This effect is indicative of an increase in endoplasmic reticulum (ER)… read more here.
Keywords: cisplatin; induced ototoxicity; cannabinoid; cisplatin induced ... See more keywords
Cannabinoid-based therapy as a future for joint degeneration. Focus on the role of CB2 receptor in the arthritis progression and pain: an updated review
Sign Up to like & getrecommendations! Published in 2021 at "Pharmacological Reports"
DOI: 10.1007/s43440-021-00270-y
Abstract: Graphic abstract Over the last several decades, the percentage of patients suffering from different forms of arthritis has increased due to the ageing population and the increasing risk of civilization diseases, e.g. obesity, which contributes… read more here.
Keywords: role cb2; cannabinoid; receptor; arthritis ... See more keywords
Activation of cannabinoid receptors elicits antidepressant-like effects in a mouse model of social isolation stress
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2017.01.018
Abstract: Social isolation stress (SIS) paradigm is a chronic stress procedure able to induce profound behavioral and neurochemical changes in rodents and evokes depressive and anxiety-like behaviors. Recent studies demonstrated that the cannabinoid system plays a… read more here.
Keywords: sis; social isolation; cannabinoid; isolation stress ... See more keywords
Cannabinoid Markers in Biological Fluids and Tissues: Revealing Intake.
Sign Up to like & getrecommendations! Published in 2018 at "Trends in molecular medicine"
DOI: 10.1016/j.molmed.2017.12.006
Abstract: Understanding cannabis and synthetic cannabinoid intake history is vital for treating drug dependence, investigating cannabinoid effects, and providing information to healthcare personnel, medical examiners, and public health officials; this is particularly relevant today with cannabis… read more here.
Keywords: markers biological; cannabinoid markers; intake; cannabinoid ... See more keywords
Long lasting effects of chronic WIN55,212-2 treatment on mesostriatal dopaminergic and cannabinoid systems in the rat brain
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.11.005
Abstract: ABSTRACT Cannabinoid administration modulates dopamine transmission via an indirect, multisynaptic mechanism that includes the activation of cannabinoid type‐1 receptor (CB1R). The present study evaluated in rodents, the effects of acute and chronic (20 days) WIN55,212–2… read more here.
Keywords: administration; chronic win55; treatment; cannabinoid ... See more keywords