Identification and biochemical analyses of selective CB2 agonists.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.03.054
Abstract: Cannabinoid CB1 and CB2 receptors are activated by Δ9-tetrahydrocannabinol, a psychoactive component of marijuana. The cannabinoid CB1 receptor is primarily located in the brain and is responsible for the psychoactive side effects, whereas the cannabinoid… read more here.
Keywords: cannabinoid cb1; cb2 receptor; cannabinoid cb2; cb2 ... See more keywords
Δ9-THC and related cannabinoids suppress substance P- induced neurokinin NK1-receptor-mediated vomiting via activation of cannabinoid CB1 receptor.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172806
Abstract: Δ9-THC suppresses cisplatin-induced vomiting through activation of cannabinoid CB1 receptors. Cisplatin-evoked emesis is predominantly due to release of serotonin and substance P (SP) in the gut and the brainstem which subsequently stimulate their corresponding 5-HT3-and… read more here.
Keywords: cannabinoid cb1; thc related; nk1 receptor; thc ... See more keywords
The Impact of CB1 Receptor on Inflammation in Skeletal Muscle Cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s322247
Abstract: Background Various factors trigger the inflammatory response and cytokine activation in skeletal muscle. Inflamed muscle will exhibit significant levels of inflammation and cytokine activity. Interleukin-6 (IL-6), a pro-inflammatory cytokine, exerts pleiotropic effects on skeletal muscle.… read more here.
Keywords: skeletal muscle; cb1 receptor; muscle; cannabinoid cb1 ... See more keywords