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Published in 2022 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.608
Abstract: As effective immune modulators, Endocannabinoids may suppress the inflammatory responses in periodontitis. This study assessed the expression of cannabinoid receptors in gingiva and the impact on periodontitis.
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Keywords:
type periodontitis;
cannabinoid receptors;
evaluation cannabinoid;
periodontitis patients ... See more keywords
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Published in 2022 at "Glia"
DOI: 10.1002/glia.24171
Abstract: In neuroscience, the explosion of innovative and advanced technical accomplishments is fundamental to understanding brain functioning. For example, the possibility to distinguish glial and neuronal activities at the synaptic level and/or the appearance of new…
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Keywords:
cannabinoid receptors;
cannabinoid;
cannabinoid signaling;
signaling behavior ... See more keywords
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Published in 2019 at "Journal of periodontology"
DOI: 10.1002/jper.18-0766
Abstract: BACKGROUND Transient receptor potential vanilloid type-1 (TRPV1) is expressed in oral tissues cells and its activity can be regulated by inflammation products and anandamide. The aim of the present study was to evaluate the effects…
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Keywords:
vanilloid type;
cannabinoid receptors;
transient receptor;
potential vanilloid ... See more keywords
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Published in 2017 at "Handbook of experimental pharmacology"
DOI: 10.1007/164_2016_105
Abstract: Cannabinoid receptors are fundamentally involved in all aspects of intestinal physiology, such as motility, secretion, and epithelial barrier function. They are part of a broader entity, the so-called endocannabinoid system which also includes their endocannabinoid…
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Keywords:
tract experimental;
cannabinoid receptors;
regulating tract;
experimental evidence ... See more keywords
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Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-61663-2_4
Abstract: The potential use of cannabinoids for therapeutic purposes is at the forefront of cannabinoid research which aims to develop innovative strategies to prevent, manage and treat a broad spectrum of human diseases. This chapter briefly reviews…
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Keywords:
disorders quest;
cannabinoid receptors;
receptors ligands;
cns disorders ... See more keywords
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Published in 2017 at "Biological Psychiatry"
DOI: 10.1016/j.biopsych.2016.07.007
Abstract: BACKGROUND Tobacco withdrawal is associated with deficits in cognitive function, including attention, working memory, and episodic memory. Understanding the neurobiological mechanisms involved in these effects is crucial because cognitive deficits during nicotine withdrawal may predict…
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Keywords:
cognitive deficits;
cannabinoid receptors;
cb1 cannabinoid;
structural plasticity ... See more keywords
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Published in 2017 at "Journal of environmental sciences"
DOI: 10.1016/j.jes.2016.05.031
Abstract: Sulfur dioxide (SO2) pollution in the atmospheric environment causes brain inflammatory insult and inflammatory-related microvasculature dysfunction. However, there are currently no effective medications targeting the harmful outcomes from chemical inhalation. Endocannabinoids (eCBs) are involved in…
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Keywords:
cannabinoid receptors;
sulfur dioxide;
dysfunction;
inflammatory ... See more keywords
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Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.09.006
Abstract: ABSTRACT Histaminergic (HA) neurons located in the tuberomamillary nucleus (TMN) of the posterior hypothalamus fire exclusively during waking and support many physiological functions. We investigated the role of the endovanilloid N‐oleoyldopamine (OLDA) in TMN, where…
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Keywords:
olda excitation;
histaminergic neurons;
cannabinoid receptors;
dopamine ... See more keywords
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Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.06.009
Abstract: &NA; Selective estrogen receptor modulators (SERMs) target estrogen receptors (ERs) to treat breast cancer and osteoporosis. Several SERMs exhibit anti‐cancer activity not related to ERs. To discover novel anti‐cancer drugs acting via ER‐independent mechanisms, derivatives…
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Keywords:
anti inflammatory;
inverse agonist;
high affinity;
affinity ... See more keywords
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Published in 2019 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2019.06.005
Abstract: Quetiapine is a common atypical antipsychotic used to treat mental disorders such as schizophrenia, bipolar disorder, and major depressive disorder. There has been increasing number of reports describing its cardiotoxicity. However, the molecular mechanisms underlying…
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Keywords:
quetiapine;
quetiapine induced;
cannabinoid receptors;
cell death ... See more keywords
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Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.1c00760
Abstract: The therapeutic potential of cannabinoid receptors is not fully explored due to psychoactive side effects and lack of selectivity associated with orthosteric ligands. Allosteric modulators have the potential to become selective therapeutics for cannabinoid receptors.…
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Keywords:
distinct binding;
cannabinoid;
mechanisms allosteric;
cannabinoid receptors ... See more keywords