Cannabinoids prevent the amyloid β‐induced activation of astroglial hemichannels: A neuroprotective mechanism
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DOI: 10.1002/glia.23080
Abstract: The mechanisms involved in Alzheimer's disease are not completely understood and how astrocytes and their gliotransmission contribute to this neurodegenerative disease remains to be fully elucidated. Previous studies have shown that amyloid‐β peptide (Aβ) induces… read more here.
Keywords: hemichannel activity; mechanism; hemichannel; amyloid induced ... See more keywords
Cannabinoids prevent the differential long‐term effects of exposure to severe stress on hippocampal‐ and amygdala‐dependent memory and plasticity
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DOI: 10.1002/hipo.22755
Abstract: Exposure to excessive or uncontrolled stress is a major factor associated with various diseases including posttraumatic stress disorder (PTSD). The consequences of exposure to trauma are affected not only by aspects of the event itself,… read more here.
Keywords: memory; amygdala dependent; prevent differential; stress ... See more keywords
Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD
Sign Up to like & getrecommendations! Published in 2018 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"
DOI: 10.1016/j.pnpbp.2018.01.026
Abstract: ABSTRACT Posttraumatic stress disorder (PTSD) is a debilitating condition highly comorbid with depression. The endocannabinoid (eCB) system and brain‐derived neurotrophic factor (BDNF) are suggestively involved in both disorders. We examined whether cannabinoids can prevent the… read more here.
Keywords: model ptsd; depressive like; like symptoms; cannabinoids prevent ... See more keywords