Validating a predictive model of cannabinoid inheritance with feral, clinical, and industrial Cannabis sativa
Sign Up to like & getrecommendations! Published in 2020 at "American Journal of Botany"
DOI: 10.1002/ajb2.1550
Abstract: Premise How genetic variation within a species affects phytochemical composition is a fundamental question in botany. The ratio of two specialized metabolites in Cannabis sativa, tetrahydrocannabinol (THC) and cannabidiol (CBD), can be grouped into three… read more here.
Keywords: botany; sativa; inheritance; model ... See more keywords
Cannabinoid Type 1 Receptor (CB1) Ligands with Therapeutic Potential for Withdrawal Syndrome in Chemical Dependents of Cannabis sativa
Sign Up to like & getrecommendations! Published in 2017 at "ChemMedChem"
DOI: 10.1002/cmdc.201700129
Abstract: Cannabis sativa withdrawal syndrome is characterized mainly by psychological symptoms. By using computational tools, the aim of this study was to propose drug candidates for treating withdrawal syndrome based on the natural ligands of the… read more here.
Keywords: cannabinoid type; type receptor; withdrawal syndrome; cannabis sativa ... See more keywords
Dual‐Function Plant‐Derived Nanovesicles From Regenerated Cannabis sativa Roots for Immunotherapy and Vaccine Delivery
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.70206
Abstract: ABSTRACT Cannabis sativa is a medicinal plant that produces a diverse array of pharmacologically active metabolites, making it a valuable resource for pharmaceutical applications. In this study, an adventitious root (AR) culture system was established… read more here.
Keywords: plant; pdnvs; cell; cannabis sativa ... See more keywords
Cannabidiol‐Rich Cannabis sativa L. Extract Alleviates LPS‐Induced Neuroinflammation Behavioral Alterations, and Astrocytic Bioenergetic Impairment in Male Mice
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.70035
Abstract: Neuroinflammation is a hallmark of various neurodegenerative disorders, yet effective treatments remain limited. This study investigates the neuroprotective potential of a cannabidiol (CBD)‐Rich Cannabis sativa L. (CS) extract in a lipopolysaccharide (LPS)‐induced neuroinflammation mouse model.… read more here.
Keywords: rich cannabis; neuroinflammation; sativa extract; cannabis sativa ... See more keywords
Ultrasound-assisted extraction of oil from hempseed (Cannabis sativa L.) - Part 2.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12205
Abstract: BACKGROUND Oilseed-matrix consolidation is a crucial factor when talking about oil expression, since, as the cake consolidates the coefficient of permeability inevitably decreases. Thus, any treatment that extensively ruptures cell walls reduces rigidity and hardness… read more here.
Keywords: cannabis sativa; oil expression; oil; extraction ... See more keywords
Simultaneous determination of terpenes and cannabidiol in hemp (Cannabis sativa L.) by fast Gas Chromatography with Flame Ionization Detection.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.201900822
Abstract: Hemp (Cannabis sativa L.) has become widely used in several sectors due to the presence of various bioactive compounds such as terpenes and cannabidiol. In general, terpenes and cannabidiol content is determined separately which is… read more here.
Keywords: hemp cannabis; detection; determination; cannabidiol hemp ... See more keywords
Emerging diseases of Cannabis sativa and sustainable management
Sign Up to like & getrecommendations! Published in 2021 at "Pest Management Science"
DOI: 10.1002/ps.6307
Abstract: Abstract Cultivation of cannabis plants (Cannabis sativa L., marijuana) has taken place worldwide for centuries. In Canada, legalization of cannabis in October 2018 for the medicinal and recreational markets has spurned interest in large‐scale growing.… read more here.
Keywords: cannabis; sativa sustainable; diseases cannabis; emerging diseases ... See more keywords
In vitro metabolism of Tebuconazole, Flurtamone, Fenhexamid, Metalaxyl-M and Spirodiclofen in Cannabis sativa L. (hemp) callus cultures.
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DOI: 10.1002/ps.6575
Abstract: BACKGROUND Cannabis sativa L. (C. sativa; hemp) is a medicinal plant producing various cannabinoids. Its consumption is legalized for medical use due to their alleged positive health effects. To satisfy the demand C. sativa plants… read more here.
Keywords: sativa; sativa hemp; metabolism; callus cultures ... See more keywords
Cannabis sativa L. extract and cannabidiol inhibit in vitro mediators of skin inflammation and wound injury
Sign Up to like & getrecommendations! Published in 2019 at "Phytotherapy Research"
DOI: 10.1002/ptr.6400
Abstract: Skin inflammatory diseases result from complex events that include dysregulation and abnormal expression of inflammatory mediators or their receptors in skin cells. The present study investigates the potential effect of a Cannabis sativa L. ethanolic… read more here.
Keywords: cannabis; inflammation; effect; cannabis sativa ... See more keywords
Non‐psychotropic Cannabis sativa L. phytocomplex modulates microglial inflammatory response through CB2 receptors‐, endocannabinoids‐, and NF‐κB‐mediated signaling
Sign Up to like & getrecommendations! Published in 2022 at "Phytotherapy Research"
DOI: 10.1002/ptr.7458
Abstract: Cannabis sativa L. is increasingly emerging for its protective role in modulating neuroinflammation, a complex process orchestrated among others by microglia, the resident immune cells of the central nervous system. Phytocannabinoids, especially cannabidiol (CBD), terpenes,… read more here.
Keywords: cannabis sativa; sativa; inflammatory response; sativa phytocomplex ... See more keywords
Bioassay-guided fractionations of Cannabis sativa extract and HPLC-assisted purifications of anti-proliferative active fractions lead to the isolation of 16 known and one new phytomolecule and their in-silico analysis
Sign Up to like & getrecommendations! Published in 2024 at "Medicinal Chemistry Research"
DOI: 10.1007/s00044-024-03199-y
Abstract: The comprehensive anti-cancer activities of cannabinoid acids and non-cannabinoids are not fully explored. Herein we report simple extraction, faster bioassay-guided fractionation, and HPLC-assisted purification of bioactive secondary metabolite and their identification. Anti-proliferative activity of six… read more here.
Keywords: non cannabinoids; hplc assisted; cannabis sativa; bioassay guided ... See more keywords