Animal evidence considered in determination of cannabis smoke and Δ9‐tetrahydrocannabinol as causing reproductive toxicity (developmental endpoint): Part III. Proposed neurodevelopmental mechanisms of action
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DOI: 10.1002/bdr2.2088
Abstract: This review summarizes the most common potential pathways of neurodevelopmental toxicity due to perinatal exposure to Δ9‐tetrahydrocannabinol (Δ9‐THC) that lead to behavioral and other adverse outcomes (AOs). This is Part III in a set of… read more here.
Keywords: exposure thc; cannabis smoke; toxicity; part iii ... See more keywords
Chemical and physical variations of cannabis smoke from a variety of cannabis samples in New Zealand
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DOI: 10.1080/20961790.2018.1445937
Abstract: ABSTRACT Studies have compared the chemical properties of tobacco smoke to those of cannabis smoke, with the objective of identifying the chemical attributes responsible for the mutagenicity and carcinogenicity of cannabis smoke. Comparative studies have… read more here.
Keywords: cannabis; cannabis samples; physical variations; chemical physical ... See more keywords
Effects of repeated adolescent exposure to cannabis smoke on cognitive outcomes in adulthood
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DOI: 10.1177/0269881120965931
Abstract: Background: Cannabis (marijuana) is the most widely used illicit drug in the USA, and consumption among adolescents is rising. Some animal studies show that adolescent exposure to delta 9-tetrahydrocannabinol or synthetic cannabinoid receptor 1 agonists… read more here.
Keywords: cognitive outcomes; exposure; exposure cannabis; adolescent exposure ... See more keywords
Development and validation of a mouse model of contemporary cannabis smoke exposure
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DOI: 10.1183/23120541.00107-2021
Abstract: Cannabis is widely used for both recreational and medicinal purposes. Inhalation of combusted cannabis smoke is the most common mode of drug consumption, exposing the lungs to the pharmacologically active ingredients, including tetrahydrocannabinol (THC) and… read more here.
Keywords: smoke exposure; contemporary cannabis; model; cannabis smoke ... See more keywords
Effect of long-acting β-agonists/glucocorticoids on human airway epithelial cell cytokine, transcriptomic and oxidative stress responses to cannabis smoke
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DOI: 10.1183/23120541.00265-2019
Abstract: Cannabis is one of the most widely consumed drugs in the world, with an estimated 180 million annual users globally [1]. Recent trends of legalisation of medicinal and/or recreational cannabis have led to increased access… read more here.
Keywords: cannabis; oxidative stress; airway epithelial; cannabis smoke ... See more keywords
Transcriptomic and barrier responses of human airway epithelial cells exposed to cannabis smoke
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DOI: 10.14814/phy2.14249
Abstract: Globally, many jurisdictions are legalizing or decriminalizing cannabis, creating a potential public health issue that would benefit from experimental evidence to inform policy, government regulations, and user practices. Tobacco smoke exposure science has created a… read more here.
Keywords: smoke; airway epithelial; human airway; tobacco smoke ... See more keywords
Standardized Cannabis Smoke Extract Induces Inflammation in Human Lung Fibroblasts
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DOI: 10.3389/fphar.2022.852029
Abstract: Cannabis (marijuana) is the most commonly used illicit product in the world and is the second most smoked plant after tobacco. There has been a rapid increase in the number of countries legalizing cannabis for… read more here.
Keywords: human lung; cannabis; smoke extract; case ... See more keywords