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   Articles with "canonical autophagy" as a keyword



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Macrophage LC3-associated phagocytosis is an immune defense against Streptococcus pneumoniae that diminishes with host aging

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recommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2015368117

Abstract: Significance The elderly exhibit susceptibility to many infectious agents, including S. pneumoniae. A robust acute inflammatory response to S. pneumoniae is associated with severe disease. S. pneumoniae triggers canonical autophagy in nonprofessional phagocytes, but its… read more here.

Keywords: lc3; defense; pneumoniae; streptococcus pneumoniae ... See more keywords
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BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection.

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recommendations! Published in 2020 at "Journal of cell science"

DOI: 10.1242/jcs.251835

Abstract: Autophagy is a degradative cellular pathway that targets cytoplasmic contents and organelles for turnover by the lysosome. Various autophagy pathways play key roles in the clearance of viral infections, and many families of viruses have… read more here.

Keywords: bpifb3; non canonical; arfgap1 tmed9; autophagy ... See more keywords
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When the Phagosome Gets Leaky: Pore-Forming Toxin-Induced Non-Canonical Autophagy (PINCA)

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recommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"

DOI: 10.3389/fcimb.2022.834321

Abstract: Macrophages remove bacteria from the extracellular milieu via phagocytosis. While most of the engulfed bacteria are degraded in the antimicrobial environment of the phagolysosome, several bacterial pathogens have evolved virulence factors, which evade degradation or… read more here.

Keywords: pore forming; canonical autophagy; pinca; non canonical ... See more keywords
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Canonical and Non-Canonical Autophagy in HIV-1 Replication Cycle

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recommendations! Published in 2017 at "Viruses"

DOI: 10.3390/v9100270

Abstract: Autophagy is a lysosomal-dependent degradative process essential for maintaining cellular homeostasis, and is a key player in innate and adaptive immune responses to intracellular pathogens such as human immunodeficiency virus type 1 (HIV-1). In HIV-1… read more here.

Keywords: canonical autophagy; hiv; non canonical; autophagy ... See more keywords