A New Bias Site for Epigenetic Modifications: How Non‐Canonical GC Base Pairs Favor Mechanochemical Cleavage of DNA
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DOI: 10.1002/bies.202000051
Abstract: Properties of non‐canonical GC base pairs and their relations with mechanochemical cleavage of DNA are analyzed. A hypothesis of the involvement of the transient GC wobble base pairs both in the mechanisms of the mechanochemical… read more here.
Keywords: base pairs; non canonical; base; cleavage dna ... See more keywords
Understanding the role of non‐Watson‐Crick base pairs in DNA–protein recognition: Structural and energetic aspects using crystallographic database analysis and quantum chemical calculation
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DOI: 10.1002/bip.23492
Abstract: Specific recognition of DNA base sequences by proteins is vital for life‐cycles of all organisms. In a large number of crystal structures of protein–DNA complexes, DNA conformation significantly deviates from the canonical B‐DNA structure. A… read more here.
Keywords: dna; base pairs; canonical base; non canonical ... See more keywords