Non-canonical DNA structures: Comparative quantum mechanical study.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2018.02.003
Abstract: A study of relative thermodynamic stability of non-canonical DNA structures (triplexes, G-quadruplexes, i-motifs) for the first time was conducted on the basis of quantum chemical DFT/B3LYP/6-31++G (d) calculations. Results of the calculations completely reproduce the… read more here.
Keywords: dna; structures comparative; canonical dna; study ... See more keywords
Exploring potentially alternative non-canonical DNA duplex structures through simulation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2018.1483839
Abstract: Abstract Hopkins proposed an alternative and chirally distinct family of double-stranded DNA (dsDNA) models that have antiparallel chains with 5′→3′ senses opposite to those of the right-handed Watson–Crick (WC) family. Termed configuration II, this family… read more here.
Keywords: potentially alternative; dna; alternative non; exploring potentially ... See more keywords
Encoding canonical DNA quadruplex structure
Sign Up to like & getrecommendations! Published in 2018 at "Science Advances"
DOI: 10.1126/sciadv.aat3007
Abstract: The remarkable architectural diversity of four-stranded DNA known as G-quadruplexes can be rationally designed. The main challenge in DNA quadruplex design is to encode a three-dimensional structure into the primary sequence, despite its multiple, repetitive… read more here.
Keywords: encoding canonical; quadruplex structure; dna quadruplex; dna ... See more keywords
Non-canonical DNA structures: Diversity and disease association
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.959258
Abstract: A complete understanding of DNA double-helical structure discovered by James Watson and Francis Crick in 1953, unveil the importance and significance of DNA. For the last seven decades, this has been a leading light in… read more here.
Keywords: structures diversity; dna; dna structures; canonical dna ... See more keywords