Ursolic acid inhibits the activation of smoothened‐independent non‐canonical hedgehog pathway in colorectal cancer by suppressing AKT signaling cascade
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DOI: 10.1002/ptr.7523
Abstract: It is being brought to light that smoothened (SMO)‐independent non‐canonical Hedgehog signaling is associated with the pathogenesis of various cancers. Ursolic acid (UA), a pentacyclic triterpenoid present in many medicinal herbs, manifests potent effectiveness against… read more here.
Keywords: signaling cascade; hedgehog; crc; non canonical ... See more keywords