Coevolved Canonical Loops Conformations of Single-Domain Antibodies: A Tale of Three Pockets Playing Musical Chairs
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DOI: 10.3389/fimmu.2022.884132
Abstract: Single-domain antibodies (sdAbs) are a promising class of biotherapeutics with unique structural traits within their paratope region. The distribution of canonical conformations explored by their complementarity determining region (CDR) loops differs to some extent from… read more here.
Keywords: cdr cdr; canonical loops; cdr; musical chairs ... See more keywords