Canonical TGFβ signaling induces collective invasion in colorectal carcinogenesis through a Snail1- and Zeb1-independent partial EMT
Sign Up to like & getrecommendations! Published in 2022 at "Oncogene"
DOI: 10.1038/s41388-022-02190-4
Abstract: Local invasion is the initial step towards metastasis, the main cause of cancer mortality. In human colorectal cancer (CRC), malignant cells predominantly invade as cohesive collectives and may undergo partial epithelial-mesenchymal transition (pEMT) at the… read more here.
Keywords: collective invasion; canonical tgf; pemt; invasion ... See more keywords
EHF promotes colorectal carcinoma progression by activating TGF‐β1 transcription and canonical TGF‐β signaling
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DOI: 10.1111/cas.14444
Abstract: ETS homologous factor (EHF) plays a critical function in epithelial cell differentiation and proliferation. However, the roles of EHF in cancer remain largely unknown. In the present study, we investigated the expression levels, precise function… read more here.
Keywords: transcription; colorectal carcinoma; crc; tgf signaling ... See more keywords
Post-Transcriptional Regulatory Crosstalk between MicroRNAs and Canonical TGF-β/BMP Signalling Cascades on Osteoblast Lineage: A Comprehensive Review
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DOI: 10.3390/ijms24076423
Abstract: MicroRNAs (miRNAs) are a family of small, single-stranded, and non-protein coding RNAs about 19 to 22 nucleotides in length, that have been reported to have important roles in the control of bone development. MiRNAs have… read more here.
Keywords: bmp; bmp signalling; signalling cascades; canonical tgf ... See more keywords