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   Articles with "caox crystal" as a keyword



Enhancer Profiling Reveals a Protective Role of RXRα Against Calcium Oxalate‐Induced Crystal Deposition and Kidney Injury

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recommendations! Published in 2025 at "Advanced Science"

DOI: 10.1002/advs.202411735

Abstract: During the formation of kidney stones, the interaction between crystals and tubular epithelial cells (TECs) leads to tubular injury and dysfunction, which in turn promote stone formation. However, the molecular mechanisms underlying these changes in… read more here.

Keywords: calcium oxalate; caox crystal; deposition; enhancer ... See more keywords

The Protective Roles of Estrogen Receptor β in Renal Calcium Oxalate Crystal Formation via Reducing the Liver Oxalate Biosynthesis and Renal Oxidative Stress-Mediated Cell Injury

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recommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2019/5305014

Abstract: Females develop kidney stones less frequently than males do. However, it is unclear if this gender difference is related to altered estrogen/estrogen receptor (ER) signaling. Here, we found that ER beta (ERβ) signals could suppress… read more here.

Keywords: caox crystal; oxalate; crystal deposition; oxalate biosynthesis ... See more keywords

Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition

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recommendations! Published in 2017 at "PLoS ONE"

DOI: 10.1371/journal.pone.0185009

Abstract: Hyperoxaluria associated with renal deposition of calcium oxalate (CaOx) crystals causes renal injury and inflammation leading to number of diseases including chronic kidney disease (CKD). It is however, not been possible to separate the renal… read more here.

Keywords: crystal deposition; male rats; deposition; caox crystal ... See more keywords

Single-Cell RNA Sequencing Analysis Reveals the Role of Macrophage-Mediated CD44–AKT–CCL2 Pathways in Renal Tubule Injury during Calcium Oxalate Crystal Formation

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recommendations! Published in 2025 at "Research"

DOI: 10.34133/research.0690

Abstract: Oxalate-induced crystalline kidney injury is a common form of crystal nephropathy. The accumulation of calcium oxalate (CaOx) crystal could lead to renal epithelium injury and inflammation. The underlying cellular events in kidney after CaOx crystal… read more here.

Keywords: caox crystal; cell; injury; crystal formation ... See more keywords