Taking a re-look at cap-binding signatures of the mRNA cap-binding protein eIF4E orthologues in trypanosomatids
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-020-03970-w
Abstract: Protein translation leading to polypeptide synthesis involves three distinct events, namely, initiation, elongation, and termination. Translation initiation is a multi-step process that is carried out by ribosomes on the mRNA with the assistance of a… read more here.
Keywords: initiation; binding signatures; translation; cap binding ... See more keywords
microRNA-induced translational control of antiviral immunity by the cap-binding protein 4EHP.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.01.030
Abstract: Type I interferons (IFNs) are critical cytokines in the host defense against invading pathogens. Sustained production of IFNs, however, is detrimental to the host, as it provokes autoimmune diseases. Thus, the expression of IFNs is… read more here.
Keywords: induced translational; protein 4ehp; binding protein; host ... See more keywords
Mutation in HvCBP20 (Cap Binding Protein 20) Adapts Barley to Drought Stress at Phenotypic and Transcriptomic Levels
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2017.00942
Abstract: CBP20 (Cap-Binding Protein 20) encodes a small subunit of the cap-binding complex (CBC), which is involved in the conserved cell processes related to RNA metabolism in plants and, simultaneously, engaged in the signaling network of… read more here.
Keywords: stress; hvcbp20; binding protein; drought stress ... See more keywords
LeishIF4E-5 Is a Promastigote-Specific Cap-Binding Protein in Leishmania
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms22083979
Abstract: Leishmania parasites cycle between sand fly vectors and mammalian hosts, transforming from extracellular promastigotes that reside in the vectors’ alimentary canal to obligatory intracellular non-motile amastigotes that are harbored by macrophages of the mammalian hosts.… read more here.
Keywords: leishif4e; cap binding; binding protein; leishmania ... See more keywords
Comprehensive Profiling of Mutations to Influenza Virus PB2 That Confer Resistance to the Cap-Binding Inhibitor Pimodivir
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DOI: 10.3390/v13071196
Abstract: Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying drug… read more here.
Keywords: pb2; inhibitor; pimodivir; resistance ... See more keywords
Translation initiation mediated by nuclear cap-binding protein complex
Sign Up to like & getrecommendations! Published in 2017 at "BMB Reports"
DOI: 10.5483/bmbrep.2017.50.4.007
Abstract: In mammals, cap-dependent translation of mRNAs is initiated by two distinct mechanisms: cap-binding complex (CBC; a heterodimer of CBP80 and 20)-dependent translation (CT) and eIF4E-dependent translation (ET). Both translation initiation mechanisms share common features in… read more here.
Keywords: cap binding; translation; dependent translation; translation initiation ... See more keywords