A Budding Yeast Model for Human Disease Mutations in the EXOSC2 Cap Subunit of the RNA Exosome.
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DOI: 10.1261/rna.078618.120
Abstract: RNA exosomopathies, a growing family of diseases, are linked to missense mutations in genes encoding structural subunits of the evolutionarily conserved, 10-subunit exoribonuclease complex, the RNA exosome. This complex consists of a 3-subunit cap, a… read more here.
Keywords: budding yeast; cap subunit; rna exosome; function ... See more keywords