Identification of small molecules capable of regulating conformational changes of telomeric G-quadruplex
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.09.114
Abstract: Abstract Design of small molecules targeted at human telomeric G-quadruplex DNA is an extremely active research area. Interestingly, the telomeric G-quadruplex is a highly polymorphic structure. Changes in its conformation upon small molecule binding may… read more here.
Keywords: capable regulating; small molecules; telomeric quadruplex; structure ... See more keywords
EMMPRIN is an emerging protein capable of regulating cancer hallmarks.
Sign Up to like & getrecommendations! Published in 2022 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202209_29771
Abstract: EMMPRIN, also known as Basigin or CD147, is a transmembrane glycoprotein member of the immunoglobulin superfamily. It is expressed basally in cells that regulate physiological processes of the cardiovascular, nervous, and immune systems. However, EMMPRIN… read more here.
Keywords: emmprin emerging; capable regulating; protein capable; emerging protein ... See more keywords